Akuammiline alkaloids are a family of monoterpene indole alkaloids of renewed medicinal
interest. These bases act as ligands for a heterogeneous group of molecular targets and …

Publisher Summary This chapter describes the structures of the alkaloids, synthesis of
alkaloids, and pharmacology of alkaloids of the Calabar bean (Physostigmu uenenosum) …

Hodgkinsine, a trimeric pyrrolidinoindoline type alkaloid, present as a major constituent of
Psychotria spp.(Rubiaceae), has shown to produce dose-dependent, naloxone reversible …

The study of bioactive molecules with asymmetric carbon atoms, molecular asymmetry, or
both, requires the preparation of optically pure enantiomers, and the determination of the …

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In a search for less flexible analogues of caproctamine (1), a diamine diamide endowed with
an interesting AChE affinity profile, we discovered compound 2, in which the terminal 2 …

Hydrolysis of the carbamate side chains in phenserine [(−) 1] and physostigmine [(−) 2]
yields the metabolite (−)-eseroline (3), and the red dye rubreserine (4) on air oxidation of the …

The natural alkaloid (‐) PHY is a reversible anticholinesterase carbamate, but in contrast, its
optical isomer (+) PHY, is a very weak anticholinesterase. We have shown that treatment of …

The following abbreviations are used in this article (only the abbreviated name and
reference to formula number are given for complex structures): ACE, angiotensin-converting …

Ach (180) is the cationic neurotransmitter that in the central and peripheral nervous systems
effects the transmission of action potentials across nerve-nerve and neuromuscular …