The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Glioblastoma (GBM) tumor microenvironment (TME) is a highly heterogeneous and complex
system, which in addition to cancer cells, consists of various resident brain and immune cells …

The recently uncovered key role of the peripheral and central nervous systems in controlling
tumorigenesis and metastasis has opened a new area of research to identify innovative …

Experience sculpts brain structure and function. Activity-dependent modulation of the
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …

Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to
control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 …

Diffuse gliomas are primary brain tumors associated with a poor prognosis. Cellular and
molecular mechanisms driving the invasive growth patterns and therapeutic resistance are …

The mechanisms underlying the multistep process of tumorigenesis can be distilled into a
logical framework involving the acquisition of functional capabilities, the so-called hallmarks …

Optic pathway glioma (OPG) occurs in as many as one-fifth of individuals with the
neurofibromatosis type 1 (NF1) cancer predisposition syndrome. Generally considered low …

Although most pathways in the mature central nervous system cannot regenerate when
injured, research beginning in the late 20th century has led to discoveries that may help …