Cartilage Lacuna‐Inspired Microcarriers Drive Hyaline Neocartilage Regeneration
SL Ding, XY Zhao, W Xiong, LF Ji, MX Jia… - Advanced …, 2023 - Wiley Online Library
Cartilage equivalents from hydrogels containing chondrocytes exhibit excellent potential in
hyaline cartilage regeneration, yet current approaches have limited success at reconstituting …
hyaline cartilage regeneration, yet current approaches have limited success at reconstituting …
Geometric Confinement-Mediated Mechanical Tension Directs Patterned Differentiation of Mouse ESCs into Organized Germ Layers
The self-organization of embryonic stem cells (ESCs) into organized tissues with three
distinct germ layers is critical to morphogenesis and early development. While the regulation …
distinct germ layers is critical to morphogenesis and early development. While the regulation …
Advances in high throughput cell culture technologies for therapeutic screening and biological discovery applications
H Ryoo, H Kimmel, E Rondo… - … & Translational Medicine, 2024 - Wiley Online Library
Cellular phenotypes and functional responses are modulated by the signals present in their
microenvironment, including extracellular matrix (ECM) proteins, tissue mechanical …
microenvironment, including extracellular matrix (ECM) proteins, tissue mechanical …
The fusion of physics and biology in early mammalian embryogenesis.
W Piszker, M Simunovic - Current topics in developmental biology, 2024 - europepmc.org
Biomechanics in embryogenesis is a dynamic field intertwining the physical forces and
biological processes that shape the first days of a mammalian embryo. From the first cell fate …
biological processes that shape the first days of a mammalian embryo. From the first cell fate …
Facile and Rapid Microcontact Printing of Additive-Free Polydimethylsiloxane for Biological Patterning Diversity
M Sun, J Zhang, T Xuanyuan, X Liu… - ACS Applied Materials & …, 2024 - ACS Publications
The development and application of micropatterning technology play a promising role in the
manipulation of biological substances and the exploration of life sciences at the microscale …
manipulation of biological substances and the exploration of life sciences at the microscale …
Soft Polyethylene Glycol Hydrogels Support Human PSC Pluripotency and Morphogenesis
Lumenogenesis within the epiblast represents a critical step in early human development,
priming the embryo for future specification and patterning events. However, little is known …
priming the embryo for future specification and patterning events. However, little is known …
Engineering Alignment Has Mixed Effects on Human Induced Pluripotent Stem Cell Differentiated Cardiomyocyte Maturation
NG Kalkunte, TE Delambre, S Sohn… - … Engineering Part A, 2023 - liebertpub.com
The potential of human induced pluripotent stem cell differentiated cardiomyocytes (hiPSC-
CMs) is greatly limited by their functional immaturity. Strong relationships exist between …
CMs) is greatly limited by their functional immaturity. Strong relationships exist between …
β-catenin mediates endodermal commitment of human ES cells via distinct transactivation functions
Background β-catenin, acting as the core effector of canonical Wnt signaling pathway, plays
a pivotal role in controlling lineage commitment and the formation of definitive endoderm …
a pivotal role in controlling lineage commitment and the formation of definitive endoderm …
Spatial cell fate manipulation of human pluripotent stem cells by controlling the microenvironment using photocurable hydrogel
Z Wang, A Numada, F Wagai, Y Oda… - …, 2024 - journals.biologists.com
Human pluripotent stem cells (hPSCs) dynamically respond to their chemical and physical
microenvironment, dictating their behavior. However, conventional in vitro studies …
microenvironment, dictating their behavior. However, conventional in vitro studies …
An in vitro culture platform for studying the effect of collective cell migration on spatial self-organization within induced pluripotent stem cell colonies
MH Kim, M Kuroda, D Ke, N Thanuthanakhun… - Journal of Biological …, 2023 - Springer
Background Human induced pluripotent stem cells (hiPSCs) provide an in vitro system to
identify the impact of cell behavior on the earliest stages of cell fate specification during …
identify the impact of cell behavior on the earliest stages of cell fate specification during …