Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents

MA El-Zahabi, H Sakr, K El-Adl, M Zayed… - Bioorganic …, 2020 - Elsevier
Thalidomide and its analogs are immunomodulatory drugs that inhibit the production of
certain inflammatory mediators associated with cancer. In the present work, a new series of …

Design and synthesis of novel 1, 2, 3-triazole-dithiocarbamate hybrids as potential anticancer agents

YC Duan, YC Ma, E Zhang, XJ Shi, MM Wang… - European journal of …, 2013 - Elsevier
A series of novel 1, 2, 3-triazole-dithiocarbamate hybrids were designed, synthesized and
evaluated for anticancer activity against four selected human tumor cell lines (MGC-803 …

Cytotoxic activity of 3-(5-phenyl-3H-[1, 2, 4] dithiazol-3-yl) chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides

T Raj, RK Bhatia, M Sharma, AK Saxena… - European journal of …, 2010 - Elsevier
6/6, 7-Substituted-3-formylchromones (8a–g) were reacted with 2 equivalents
thiobenzamide (9) in refluxing toluene to furnish substituted-3-(5-phenyl-3H-[1, 2, 4] dithiazol …

Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer's Disease

R Venkatesh, G Shankar, AC Narayanan… - The Journal of …, 2022 - ACS Publications
Multicomponent synthesis of biologically relevant S-benzyl dithiocarbamates from para-
quinone methides, amines, and carbon disulfide are described under catalyst and additive …

Design, synthesis and antiproliferative activity studies of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids

YC Duan, YC Zheng, XC Li, MM Wang, XW Ye… - European journal of …, 2013 - Elsevier
A series of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids were designed, synthesized
and their antiproliferative activities against four selected human cancer cell lines were …

Dithiocarbamate salts: biological activity, preparation, and utility in organic synthesis

AA Aly, AB Brown, TMI Bedair… - Journal of Sulfur …, 2012 - Taylor & Francis
Full article: Dithiocarbamate salts: biological activity, preparation, and utility in organic
synthesis Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …

[HTML][HTML] Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity

SM El-Sonbaty - Cancer Nanotechnology, 2013 - Springer
Silver nanoparticles (AgNPs) were biologically synthesized using aqueous extract of
Agaricus bisporus fungi. Physicochemical analysis of silver nanoparticles revealed that they …

Effect of atorvastatin and methotrexate on solid Ehrlich tumor

AM Kabel, MN Abdel-Rahman, AEDE El-Sisi… - European journal of …, 2013 - Elsevier
Hydroxymethyl glutaryl CoA reductase is the key enzyme in cholesterol synthesis. A
relationship was found between cholesterol and the development of many types of cancer …

Coumarin derivatives as anti-inflammatory and anticancer agents

V Thomas, D Giles… - Anti-Cancer Agents …, 2017 - ingentaconnect.com
Background: Inflammation substantially contributes to the development and progression of
malignancies. cancer-related inflammation, has been proposed to promote tumor …

Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice

AA Adwas, AA Elkhoely, AM Kabel… - Journal of Infection and …, 2016 - Elsevier
Doxorubicin (DOX) is a broad-spectrum antitumor antibiotic used in treatment of cancer. Its
effect may be complicated by increased risk of cardiotoxicity. It was suggested that natural …