Roles of heat shock proteins in apoptosis, oxidative stress, human inflammatory diseases, and cancer

PC Ikwegbue, P Masamba, BE Oyinloye, AP Kappo - Pharmaceuticals, 2017 - mdpi.com
Heat shock proteins (HSPs) play cytoprotective activities under pathological conditions
through the initiation of protein folding, repair, refolding of misfolded peptides, and possible …

The pivotal role of airway smooth muscle in asthma pathophysiology

A Ozier, B Allard, I Bara, PO Girodet, T Trian… - Journal of …, 2011 - Wiley Online Library
Asthma is characterized by the association of airway hyperresponsiveness (AHR),
inflammation, and remodelling. The aim of the present article is to review the pivotal role of …

Shipping noise affecting immune responses of European spiny lobster (Palinurus elephas)

M Celi, F Filiciotto, M Vazzana, V Arizza… - Canadian Journal of …, 2015 - cdnsciencepub.com
Marine crustaceans are influenced by numerous environmental factors. Environmental
stress from pollutants seems to affect their metabolism, growth, moulting, survival, and …

Small heat shock proteins in smooth muscle

S Salinthone, M Tyagi, WT Gerthoffer - Pharmacology & therapeutics, 2008 - Elsevier
The small heat shock proteins (HSPs) HSP20, HSP27 and αB-crystallin are chaperone
proteins that are abundantly expressed in smooth muscles are important modulators of …

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins

S Carra, V Crippa, P Rusmini, A Boncoraglio… - Progress in …, 2012 - Elsevier
Motor neuron diseases (MNDs) are neurodegenerative disorders that specifically affect the
survival and function of upper and/or lower motor neurons. Since motor neurons are …

Transcriptome assembly and identification of genes and SNPs associated with growth traits in largemouth bass (Micropterus salmoides)

S Li, H Liu, J Bai, X Zhu - Genetica, 2017 - Springer
Growth is one of the most crucial economic traits of all aquaculture species, but the
molecular mechanisms involved in growth of largemouth bass (Micropterus salmoides) are …

[HTML][HTML] Contribution of small heat shock proteins to muscle development and function

M Dubińska-Magiera, J Jabłońska, J Saczko… - FEBS letters, 2014 - Elsevier
Investigations undertaken over the past years have led scientists to introduce the concept of
protein quality control (PQC) systems, which are responsible for polypeptide processing …

Chaperone function and mechanism of small heat-shock proteins

X Fu - Acta Biochim Biophys Sin, 2014 - academic.oup.com
Small heat-shock proteins (sHSPs) are ubiquitous ATP-independent molecular chaperones
that play crucial roles in protein quality control in cells. They are able to prevent the …

In vivo substrate diversity and preference of small heat shock protein IbpB as revealed by using a genetically incorporated photo-cross-linker

X Fu, X Shi, L Yan, H Zhang, Z Chang - Journal of Biological Chemistry, 2013 - ASBMB
Small heat shock proteins (sHSPs), as ubiquitous molecular chaperones found in all forms
of life, are known to be able to protect cells against stresses and suppress the aggregation of …

Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells

DL Milton, AN Schneck, DA Ziech… - Proceedings of the …, 2011 - National Acad Sciences
The 10S self-inhibited monomeric conformation of myosin II has been characterized
extensively in vitro. Based upon its structural and functional characteristics, it has been …