Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …

Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting
in elevated cost for public health systems. DN is the main cause of chronic kidney disease …

Introduction: Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in
diabetes and is the most common cause of proteinuric and non-proteinuric forms of end …

Diabetic kidney disease (DKD) is a chronic complication of diabetes mellitus which may
eventually lead to end‐stage kidney disease (ESKD). Despite improvements in glycaemic …

Relaxin is an antifibrotic peptide hormone previously assumed to directly reverse the
activation of hepatic stellate cells for liver fibrosis resolution. Using nanoparticle-mediated …

Chronic kidney disease (CKD) is a major public health concern, underscoring a need to
identify pathogenic mechanisms and potential therapeutic targets. Reactive oxygen species …

Oxygen is required to sustain aerobic organisms. Reactive oxygen species (ROS) are
constantly released during mitochondrial oxygen consumption for energy production. Any …

Diabetic kidney disease remains the most common cause of end-stage kidney disease in
the world. Despite reductions in incidence rates of myocardial infarction and stroke in people …

Background Depression, as a prevalent and debilitating psychiatric disease, severely
decreases the life quality of individuals and brings heavy burdens to the whole society …