Integrating gene annotation with orthology inference at scale

BM Kirilenko, C Munegowda, E Osipova, D Jebb… - Science, 2023 - science.org
Annotating coding genes and inferring orthologs are two classical challenges in genomics
and evolutionary biology that have traditionally been approached separately, limiting …

[HTML][HTML] Diagnostic and therapeutic value of human serpin family proteins

S Janciauskiene, U Lechowicz, M Pelc… - Biomedicine & …, 2024 - Elsevier
SERPIN (serine proteinase inhibitors) is an acronym for the superfamily of structurally similar
proteins found in animals, plants, bacteria, viruses, and archaea. Over 1500 SERPINs are …

Diversified mammalian visual adaptations to bright-or dim-light environments

Y Gai, R Tian, F Liu, Y Mu, L Shan… - Molecular Biology …, 2023 - academic.oup.com
Photic niche shifts of mammals are associated with changing visual capabilities, primarily
mediated by three visual pigments, two (SWS1 and M/LWS) of them for color vision and …

[HTML][HTML] The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

SF Abcouwer, B Miglioranza Scavuzzi, PE Kish… - Journal of …, 2024 - Springer
The retinal pigment epithelium (RPE) maintains photoreceptor viability and function,
completes the visual cycle, and forms the outer blood-retinal barrier (oBRB). Loss of RPE …

[HTML][HTML] Poor eyesight reveals a new vision gene

T Biswas, J Krishnan, N Rohner - Elife, 2022 - elifesciences.org
Evolution: Poor eyesight reveals a new vision gene | eLife Skip to Content eLife logo eLife
home page Menu Home Magazine Community About Search Alerts Submit your research …

[HTML][HTML] Decay of skin-specific gene modules in pangolins

B Pinto, R Valente, F Caramelo, R Ruivo… - Journal of Molecular …, 2023 - Springer
The mammalian skin exhibits a rich spectrum of evolutionary adaptations. The
pilosebaceous unit, composed of the hair shaft, follicle, and the sebaceous gland, is the …

Gene loss and relaxed selection of plaat1 in vertebrates adapted to low-light environments

DH Drabeck, J Wiese, E Gilbertson… - … of the Royal …, 2024 - royalsocietypublishing.org
Gene loss is an important mechanism for evolution in low-light or cave environments where
visual adaptations often involve a reduction or loss of eyesight. The plaat gene family …

[HTML][HTML] Accelerated evolution of dim-light vision-related arrestin in deep-diving amniotes

X Guo, Y Cui, DM Irwin, Y Liu - Frontiers in Ecology and Evolution, 2022 - frontiersin.org
Arrestins are key molecules involved in the signaling of light-sensation initiated by visual
pigments in retinal photoreceptor cells. Vertebrate photoreceptor cells have two types of …

Convergent Decay of Skin-specific Gene Modules in Pangolins

B Pinto, R Valente, F Caramelo, R Ruivo, LFC Castro - bioRxiv, 2022 - biorxiv.org
The Mammalia skin exhibits a rich spectrum of evolutionary adaptations. The pilosebaceous
unit, composed of the hair shaft, follicle, and the sebaceous gland, is the most striking …

Identifying the Genomic Basis of Biological Variation.

DP Genereux - CHOICE: Current Reviews for Academic Libraries, 2023 - go.gale.com
Identifying the Genomic Basis of Biological Variation. - Document - Gale Literature
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