Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

Fate and freedom in developing neocortical circuits

D Jabaudon - Nature communications, 2017 - nature.com
The activity of neuronal circuits of the neocortex underlies our ability to perceive the world
and interact with our environment. During development, these circuits emerge from dynamic …

Genetic dissection of the glutamatergic neuron system in cerebral cortex

KS Matho, D Huilgol, W Galbavy, M He, G Kim, X An… - Nature, 2021 - nature.com
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …

Molecular mechanisms controlling vertebrate retinal patterning, neurogenesis, and cell fate specification

X Zhang, P Leavey, H Appel, N Makrides… - Trends in Genetics, 2023 - cell.com
This review covers recent advances in understanding the molecular mechanisms controlling
neurogenesis and specification of the developing retina, with a focus on insights obtained …

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

K Harb, E Magrinelli, CS Nicolas, N Lukianets… - Elife, 2016 - elifesciences.org
During cortical development, the identity of major classes of long-distance projection
neurons is established by the expression of molecular determinants, which become …

Lhx2 is an essential factor for retinal gliogenesis and notch signaling

J de Melo, C Zibetti, BS Clark, W Hwang… - Journal of …, 2016 - Soc Neuroscience
Müller glia (MG) are the only glial cell type produced by the neuroepithelial progenitor cells
that generate the vertebrate retina. MG are required to maintain retinal homeostasis and …

How the barrel cortex became a working model for developmental plasticity: a historical perspective

RS Erzurumlu, P Gaspar - Journal of Neuroscience, 2020 - Soc Neuroscience
For half a century now, the barrel cortex of common laboratory rodents has been an
exceptionally useful model for studying the formation of topographically organized maps …

The cortical hem regulates the size and patterning of neocortex

G Caronia-Brown, M Yoshida, F Gulden… - …, 2014 - journals.biologists.com
The cortical hem, a source of Wingless-related (WNT) and bone morphogenetic protein
(BMP) signaling in the dorsomedial telencephalon, is the embryonic organizer for the …

[HTML][HTML] Lhx2, an evolutionarily conserved, multifunctional regulator of forebrain development

SJ Chou, S Tole - Brain research, 2019 - Elsevier
A hundred years after Lhx2 ortholog apterous was identified as a critical regulator of wing
development in Drosophila, LIM-HD gene family members have proved to be versatile and …

LHX2 interacts with the NuRD complex and regulates cortical neuron subtype determinants Fezf2 and Sox11

B Muralidharan, Z Khatri, U Maheshwari… - Journal of …, 2017 - Soc Neuroscience
In the developing cerebral cortex, sequential transcriptional programs take neuroepithelial
cells from proliferating progenitors to differentiated neurons with unique molecular identities …