The roles of microRNAs in epigenetic regulation

Q Yao, Y Chen, X Zhou - Current opinion in chemical biology, 2019 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs, approximately 18–25 nucleotides in
length, now recognized as one of the major regulatory gene families in eukaryotes. Recent …

Interplay between miRNAs and human diseases

P Paul, A Chakraborty, D Sarkar… - Journal of cellular …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, non‐coding RNAs, which have evoked a great deal
of interest due to their importance in many aspects of homeostasis and diseases …

MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

MicroRNAs in stress signaling and human disease

JT Mendell, EN Olson - Cell, 2012 - cell.com
Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

MicroRNAs in obesity and related metabolic disorders

JF Landrier, A Derghal, L Mounien - Cells, 2019 - mdpi.com
Metabolic disorders are characterized by the inability to properly use and/or store energy.
The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …

[HTML][HTML] MicroRNAs: synthesis, mechanism, function, and recent clinical trials

F Wahid, A Shehzad, T Khan, YY Kim - Biochimica et Biophysica Acta (BBA …, 2010 - Elsevier
MicroRNAs (miRNAs) are a class of small, endogenous RNAs of 21–25 nucleotides (nts) in
length. They play an important regulatory role in animals and plants by targeting specific …

The functions of animal microRNAs

V Ambros - Nature, 2004 - nature.com
MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …

[HTML][HTML] MicroRNAs: genomics, biogenesis, mechanism, and function

DP Bartel - cell, 2004 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 22 nt RNAs that can play important regulatory
roles in animals and plants by targeting mRNAs for cleavage or translational repression …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

MicroRNAs: small RNAs with a big role in gene regulation

L He, GJ Hannon - Nature reviews genetics, 2004 - nature.com
MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a
sequence-specific manner. The two founding members of the microRNA family were …