The levels of aspartate aminotransferase (AST/GOT) and alanine aminotransferase
(ALT/GPT) in serum can help people diagnose body tissues especially the heart and the …

In pharmaceutical research, an adequate cell-based assay scheme to efficiently screen and
to validate potential drug candidates in the initial stage of drug discovery is crucial. In order …

The dynamics governing gene regulation have an important role in determining the
phenotype of a cell or organism. From processing extracellular signals to generating internal …

This work describes the development and investigation of an aptamer modified microfluidic
device that captures rare cells to achieve a rapid assay without pretreatment of cells. To …

The investigation of human disease mechanisms is difficult due to the heterogeneity in gene
expression and the physiological state of cells in a given population. In comparison to bulk …

Positioning single cells is of utmost importance in areas of biomedical research as diverse
as in vitro fertilization, cell-cell interaction, cell adhesion, embryology, microbiology, stem …

There is a growing need for efficient mesenchymal stem cell (MSC) production processes for
a wide spectrum of clinical conditions ranging from the treatment of life‐threatening graft …

Abstract Poly (dimethylsiloxane)(PDMS) has a long history of exploitation in a variety of
biological and medical applications. Particularly in the past decade, PDMS has attracted …

We present a modular system of microfluidic PDMS devices designed to incorporate the
steps necessary for cell biological assays based on mammalian tissue culture 'on-chip'. The …

This paper presents the design, fabrication, and characterization of a microfluidic biochip
with integrated actuation electrodes used to manipulate a cell and a microbead by …