Integrons are genetic elements involved in bacterial adaptation which capture, shuffle and
express genes encoding adaptive functions embedded in cassettes. These events are …

To preserve the integrity of their genome, bacteria rely on several genome maintenance
mechanisms that are co-ordinated with the cell cycle. All members of the Vibrio family have a …

This chapter reviews the current knowledge on the organization and replication of bacterial
genomes with a special emphasis on the initiation of DNA replication. Most bacteria contain …

Replication of Vibrio cholerae chromosome 2 (Chr2) initiates when the Chr1 locus, crtS (C
hr2 r eplication t riggering s ite) duplicates. The site binds the Chr2 initiator, RctB, and the …

Integrons confer a rapid adaptation capability to bacteria. Integron integrases are able to
capture and shuffle novel functions embedded in cassettes. Here, we investigated cassette …

It is unclear how gene order within the chromosome influences genome evolution. Bacteria
cluster transcription and translation genes close to the replication origin (oriC). In Vibrio …

Studies of bacterial chromosomes and plasmids indicate that their replication initiator
proteins bind to origins of replication at many double-stranded sites and also at AT-rich …

Bacterial chromosomes harbour a unique origin of bidirectional replication, oriC. They are
almost always circular, with replication terminating in a region diametrically opposite to oriC …

Vibrio cholerae, the pathogenic bacterium that causes cholera, has two chromosomes
(Chr1, Chr2) that replicate in a well-orchestrated sequence. Chr2 initiation is triggered only …

Chromosomal inheritance in bacteria usually entails bidirectional replication of a single
chromosome from a single origin into two copies and subsequent partitioning of one copy …