Strategies for the chemical and biological functionalization of scaffolds for cardiac tissue engineering: a review

M Tallawi, E Rosellini, N Barbani… - Journal of the …, 2015 - royalsocietypublishing.org
The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …

The role of ACE2 in cardiovascular physiology

GY Oudit, MA Crackower, PH Backx… - Trends in cardiovascular …, 2003 - Elsevier
The renin–angiotensin system (RAS) is critically involved in cardiovascular and renal
function and in disease conditions, and has been shown to be a far more complex system …

Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

T Oyama, T Nagai, H Wada, AT Naito… - The Journal of cell …, 2007 - rupress.org
Side population (SP) cells, which can be identified by their ability to exclude Hoechst 33342
dye, are one of the candidates for somatic stem cells. Although bone marrow SP cells are …

Cardiac specific differentiation of mouse embryonic stem cells

A Sachinidis, BK Fleischmann, E Kolossov… - Cardiovascular …, 2003 - academic.oup.com
Embryonic stem (ES) cells may represent an alternative source of functionally intact
cardiomyocytes for the causal treatment of cardiovascular diseases. However, this requires …

Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro

BC Heng, HK Haider, EKW Sim, T Cao… - Cardiovascular …, 2004 - academic.oup.com
Most studies on stem cell transplantation therapy on myocardially infarcted animal models
and phase-I human clinical trials have focused on the use of undifferentiated stem cells …

[HTML][HTML] Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation

A Kruzynska-Frejtag, M Machnicki, R Rogers… - Mechanisms of …, 2001 - Elsevier
Periostin was originally isolated as a osteoblast-specific factor that functions as a cell
adhesion molecule for preosteoblasts and is thought to be involved in osteoblast …

Cellular Internalization of Poly(ethylene oxide)-b-poly(ε-caprolactone) Diblock Copolymer Micelles

L Luo, J Tam, D Maysinger, A Eisenberg - Bioconjugate chemistry, 2002 - ACS Publications
Poly (ethylene oxide)-b-poly (ε-caprolactone)(PEO-b-PCL) block copolymers self-assemble
into micelles in aqueous solution. We have examined whether these micelles can internalize …

Enhancing the outcome of cell therapy for cardiac repair: progress from bench to bedside and back

E Chavakis, M Koyanagi, S Dimmeler - Circulation, 2010 - Am Heart Assoc
expanded from cardiac biopsies by different protocols. 9, 10 Very recently, the first patients
were treated with either cardiosphere-derived cardiac stem cells (CArdiosphere-Derived …

G protein‐coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function

A Tadevosyan, G Vaniotis, BG Allen… - The Journal of …, 2012 - Wiley Online Library
G protein‐coupled receptors (GPCRs) play key physiological roles in numerous tissues,
including the heart, and their dysfunction influences a wide range of cardiovascular …

Stem cells as a source of regenerative cardiomyocytes

K Fukuda, S Yuasa - Circulation research, 2006 - Am Heart Assoc
The realization of regenerative cardiac medicine depends on the availability of
cardiomyocytes in sufficient numbers for transplantation of cardiac tissue and the …