Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcal Disease in Diverse Hosts

DB Meya, PR Williamson - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …

Overcoming clinical challenges in the management of invasive fungal infections in low-and middle-income countries (LMIC)

A Chakrabarti, AK Patel, R Soman… - Expert Review of Anti …, 2023 - Taylor & Francis
Introduction The management of invasive fungal infections (IFIs) in low-and middle-income
countries (LMIC) is a serious challenge due to limited epidemiology studies, sub-optimal …

Frequency of fungal pathogens in autopsy studies of people who died with HIV in Africa: a scoping review

F Bongomin, W Kibone, L Atulinda, B Morgan… - Clinical Microbiology …, 2024 - Elsevier
Background Fungal infections are common in HIV-infected individuals and significantly
contribute to mortality. However, a substantial number of cases are undiagnosed before …

Cryptococcosis in Africa: What the data tell us

C Ibe, CA Okoye, E Nweze, A Otu - Medical Mycology, 2023 - academic.oup.com
Cryptococcosis is a neglected tropical disease and the main cause of fungal-related deaths
in HIV-positive persons in Africa. It is an AIDS-defining illness that has almost surpassed …

COVID-19, HIV-associated cryptococcal meningitis, disseminated tuberculosis and acute ischaemic stroke: a fatal foursome

F Bongomin, SG Sereke, J Okot… - Infection and drug …, 2021 - Taylor & Francis
Background Several viral, bacterial and fungal co-infections have been associated with
increased morbidity and mortality among patients with COVID-19. We report a fatal case of …

Clinical characteristics and morbidity among hospitalized adults with advanced HIV disease in Uganda during 'test and treat'era

L Tugume, FC Semitala, D Owachi… - PLOS Global Public …, 2023 - journals.plos.org
Nearly four decades after the first case of AIDS was described, the global number of AIDS-
related deaths has steadily declined but falls short of the elimination targets, especially in …

Calcimycin Inhibits Cryptococcus neoformans In Vitro and In Vivo by Targeting the Prp8 Intein Splicing

AM Tharappel, Z Li, YC Zhu, X Wu… - ACS infectious …, 2022 - ACS Publications
Drug resistance is a significant concern in the treatment of diseases, including
cryptococcosis caused by Cryptococcus neoformans (Cne) and Cryptococcus gattii (Cga) …

Neuromeningeal cryptococcosis and tuberculosis coinfection in Bamako: a one-year case series

D Ouedraogo, Y Cissoko, M Soumare… - Open Forum …, 2023 - academic.oup.com
Cryptococcosis and tuberculosis are life-threatening opportunistic infections that occur in
apparently immunocompetent or severely immunocompromised individuals worldwide. As …

[HTML][HTML] Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: a clinician's perspective

J Kasibante, MK Rutakingirwa, E Kagimu… - Journal of Clinical …, 2020 - Elsevier
As part of the END TB strategy, the World Health organization (WHO) recommends provision
of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB …