Inflammation and resolution in obesity

M Soták, M Clark, BE Suur, E Börgeson - Nature Reviews …, 2024 - nature.com
Inflammation is an essential physiological defence mechanism, but prolonged or excessive
inflammation can cause disease. Indeed, unresolved systemic and adipose tissue …

Targeting the NLRP3 inflammasome–IL-1β pathway in type 2 diabetes and obesity

DT Meier, J de Paula Souza, MY Donath - Diabetologia, 2024 - Springer
Increased activity of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
inflammasome–IL-1β pathway is observed in obesity and contributes to the development of …

A Multifunctional Bimetallic Nanoplatform for Synergic Local Hyperthermia and Chemotherapy Targeting HER2‐Positive Breast Cancer

L Zhao, F Chang, Y Tong, J Yin, J Xu, H Li… - Advanced …, 2024 - Wiley Online Library
Anti‐HER2 (human epidermal growth factor receptor 2) therapies significantly increase the
overall survival of patients with HER2‐positive breast cancer. Unfortunately, a large fraction …

[HTML][HTML] A transdiagnostic and diagnostic-specific approach on inflammatory biomarkers in eating disorders: A meta-analysis and systematic review

C Dani, L Tarchi, E Cassioli, E Rossi, GP Merola… - Psychiatry …, 2024 - Elsevier
Eating disorders (EDs) are severe mental illnesses with a multifactorial etiology and a
chronic course. Among the biological factors related to pathogenesis and maintenance of …

[HTML][HTML] T4 apoptosis in the acute phase of SARS-CoV-2 infection predicts long COVID

R Cezar, L Kundura, S André, JY Lefrant… - Frontiers in …, 2024 - frontiersin.org
Background As about 10% of patients with COVID-19 present sequelae, it is important to
better understand the physiopathology of so-called long COVID. Method To this aim, we …

Metabolic reprogramming in nasopharyngeal carcinoma: Mechanisms and therapeutic opportunities

Q Liu, AM Bode, X Chen, X Luo - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
The high prevalence of metabolic reprogramming in nasopharyngeal carcinoma (NPC)
offers an abundance of potential therapeutic targets. This review delves into the distinct …

Effect of serum concentrations of IL-6 and TNF-α on brain structure in anorexia nervosa: a combined cross-sectional and longitudinal study

F Bernardoni, F Tam, DM Poitz, I Hellerhoff… - …, 2024 - nature.com
Previous studies of brain structure in anorexia nervosa (AN) have reported reduced gray
matter in underweight patients, which largely normalizes upon weight gain. One underlying …

Luteolin-mediated phosphoproteomic changes in chicken splenic lymphocytes: unraveling the detoxification mechanisms against ammonia-induced stress

D Chen, H Tang, J Liu, H Zhang, K Rao, X Teng… - Journal of Hazardous …, 2024 - Elsevier
Long-term exposure to high ammonia concentrations could severely impact chicken health.
On the other hand, luteolin has been shown to protect against ammonia poisoning. Although …

The role of IL-1 family cytokines in diabetic cardiomyopathy

Q Wu, Y Zeng, K Geng, M Guo, F Teng, P Yan, Y Lei… - Metabolism, 2025 - Elsevier
Diabetic cardiomyopathy (DCM) is the primary cause of heart failure in patients with
diabetes and is characterised by contractile dysfunction and left ventricular hypertrophy. The …

[HTML][HTML] Conjugated bile acids alleviate acute pancreatitis through inhibition of TGR5 and NLRP3 mediated inflammation

Z Zhang, X Guo, J Liu, Y Gu, X Ji, S Zhu, J Xie… - Journal of Translational …, 2024 - Springer
Introduction Severe acute pancreatitis (SAP) is a crucial gastrointestinal disease
characterized by systemic inflammatory responses and persistent multiple organ failure. The …