Introduction The infection fatality rate (IFR) of COVID-19 has been carefully measured and
analysed in high-income countries, whereas there has been no systematic analysis of age …

The causative agent of tuberculosis (TB), Mycobacterium tuberculosis and more recently
totally drug‐resistant strains of M. tuberculosis, display unique mechanisms to survive in the …

Background Tuberculosis (TB) is a major contributor to the global burden of disease and has
received considerable attention in recent years, particularly in low-and middle-income …

New drugs are required to counter the tuberculosis (TB) pandemic. Here, we describe the
synthesis and characterization of 1, 3-benzothiazin-4-ones (BTZs), a new class of …

All tuberculosis vaccines currently in clinical trials are designed as prophylactic vaccines
based on early expressed antigens. We have developed a multistage vaccination strategy in …

ABSTRACT In total, 521 nonrespiratory specimens (91 urine, 30 gastric aspirate, 245 tissue,
113 pleural fluid, 19 cerebrospinal fluid [CSF], and 23 stool specimens) submitted to the …

Background There is no consensus whether tobacco smoking increases risk of tuberculosis
(TB) infection, disease, or mortality. Whether this is so has substantial implications for …

Tuberculosis (TB), an illness that mainly affects the respiratory system, is one of the world's
most pernicious diseases. TB currently infects one-third of the world's population and kills …

The nervous system maintains physiological homeostasis through reflex pathways that
modulate organ function. This process begins when changes in the internal milieu (eg …

Prediction of metabolic changes that result from genetic or environmental perturbations has
several important applications, including diagnosing metabolic disorders and discovering …