The puzzling mutational landscape of the SARS‐2‐variant Omicron

J Fantini, N Yahi, P Colson, H Chahinian… - Journal of medical …, 2022 - Wiley Online Library
The recently emerging SARS‐CoV‐2 variant omicron displays an unusual association of 30
mutations, 3 deletions, and 1 insertion. To analyze the impact of this atypic mutational …

Molecular dynamics studies reveal structural and functional features of the SARS‐CoV‐2 spike protein

L Pipitò, RM Rujan, CA Reynolds, G Deganutti - BioEssays, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus is responsible for the COVID‐19 pandemic the world experience
since 2019. The protein responsible for the first steps of cell invasion, the spike protein, has …

COVID-19 oral sequelae: persistent gustatory and saliva secretory dysfunctions after recovery from Covid-19

H Tsuchiya - Medical Principles and Practice, 2023 - karger.com
Diverse manifestations have been recognized to last for a long time in patients infected with
SARS-CoV-2. However, understanding of oral sequelae after recovery from COVID-19 is …

[HTML][HTML] Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants

B Tu, H Wang, X An, J Qu, Q Li, Y Gao… - Acta Pharmaceutica …, 2022 - ncbi.nlm.nih.gov
As of January 27, 2022, there were 363,062,293 cases and 5,645,884 deaths from the
COVID-19 pandemic 1. The prevalent mutated strains have aggravated the global pandemic …

[HTML][HTML] A pathway model to understand the evolution of spike protein binding to ACE2 in SARS-CoV-2 variants

L Pipitò, CA Reynolds, JC Mobarec, O Vickery… - Biomolecules, 2022 - mdpi.com
After the SARS-CoV-2 Wuhan variant that gave rise to the pandemic, other variants named
Delta, Omicron, and Omicron-2 sequentially became prevalent, with mutations spread …

[HTML][HTML] From free binding energy calculations of SARS-CoV-2—receptor interactions to cellular immune responses

MO Glocker, KFM Opuni, HJ Thiesen - Medicina, 2022 - mdpi.com
Our study focuses on free energy calculations of SARS-CoV-2 spike protein receptor binding
motives (RBMs) from wild type and variants of concern (VOCs), with emphasis on SARS …

Omicron variant of COVID-19: A focused review of biologic, clinical, and epidemiological changes

H Majlesi, S Shahsavan, Y Farsi, A Tamimi… - Immunopathologia …, 2022 - immunopathol.com
On 25 November 2021, the world health organization listed Omicron as a newly arisen and
the fifth variant of concern (VoC) of severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Is the Stalk of the SARS-CoV-2 Spike Protein Druggable?

L Pipitò, CA Reynolds, G Deganutti - Viruses, 2022 - mdpi.com
The spike protein is key to SARS-CoV-2 high infectivity because it facilitates the receptor
binding domain (RBD) encounter with ACE2. As targeting subunit S1 has not yet delivered …

[图书][B] Studies in Computational Biophysics: SARS-CoV-2 and Plant Cell Plate Maturation

MZ Jawaid - 2022 - search.proquest.com
This dissertation is split into two parts. In part 1, we discuss plant cytokinesis, a fundamental
process of plant life which involves de novo formation of a “cell plate” partitioning the …

Is the Stalk of the SARS-CoV-2 Spike Protein Druggable? Viruses 2022, 14, 2789

L Pipitò, CA Reynolds, G Deganutti - 2022 - europepmc.org
The spike protein is key to SARS-CoV-2 high infectivity because it facilitates the receptor
binding domain (RBD) encounter with ACE2. As targeting subunit S1 has not yet delivered …