Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …

The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

Our goal was to understand the impact of regenerative therapies on the functional capacity
of skeletal muscle following volumetric muscle loss (VML) injury. An extensive database …

This review identifies some key concepts of muscle regeneration, viewed from perspectives
of classical and modern research. Early insights noted the pattern and sequence of …

Volumetric muscle loss (VML) is the surgical or traumatic loss of skeletal muscle, which can
cause loss of limb function or permanent disability. VML injuries overwhelms the …

Severe traumatic skeletal muscle injuries, such as volumetric muscle loss (VML), result in
the obliteration of large amounts of skeletal muscle and lead to permanent functional …

Volumetric muscle loss (VML) is a traumatic loss of muscle tissue that results in chronic
functional impairment. When injured, skeletal muscle is capable of small‐scale repair; …

Volumetric muscle loss (VML) is traumatic or surgical loss of skeletal muscle with resultant
functional impairment. Skeletal muscle's innate capacity for regeneration is lost with VML …

Severe injuries to skeletal muscles, including cases of volumetric muscle loss (VML), are
linked to substantial tissue damage, resulting in functional impairment and lasting disability …

Engineering biomimetic tissue implants with human induced pluripotent stem cells (hiPSCs)
holds promise for repairing volumetric tissue loss. However, these implants face challenges …