Current challenges and best-practice protocols for microbiome analysis

R Bharti, DG Grimm - Briefings in bioinformatics, 2021 - academic.oup.com
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR

RD Olson, R Assaf, T Brettin, N Conrad… - Nucleic acids …, 2023 - academic.oup.com
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …

Clinical detection and characterization of bacterial pathogens in the genomics era

PE Fournier, G Dubourg, D Raoult - Genome medicine, 2014 - Springer
The availability of genome sequences obtained using next-generation sequencing (NGS)
has revolutionized the field of infectious diseases. Indeed, more than 38,000 bacterial and …

The ontology for biomedical investigations

A Bandrowski, R Brinkman, M Brochhausen, MH Brush… - PloS one, 2016 - journals.plos.org
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with
precisely defined meanings to describe all aspects of how investigations in the biological …

Finding our way through phenotypes

AR Deans, SE Lewis, E Huala, SS Anzaldo… - PLoS …, 2015 - journals.plos.org
Despite a large and multifaceted effort to understand the vast landscape of phenotypic data,
their current form inhibits productive data analysis. The lack of a community-wide …

Characterizing the genetic basis of bacterial phenotypes using genome-wide association studies: a new direction for bacteriology

TD Read, RC Massey - Genome medicine, 2014 - Springer
Genome-wide association studies (GWASs) have become an increasingly important
approach for eukaryotic geneticists, facilitating the identification of hundreds of genetic …

Future-proofing and maximizing the utility of metadata: The PHA4GE SARS-CoV-2 contextual data specification package

EJ Griffiths, RE Timme, CI Mendes, AJ Page… - …, 2022 - academic.oup.com
Abstract Background The Public Health Alliance for Genomic Epidemiology
(PHA4GE)(https://pha4ge. org) is a global coalition that is actively working to establish …

The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability

Y He, Z Xiang, J Zheng, Y Lin, JA Overton… - Journal of biomedical …, 2018 - Springer
Ontologies are critical to data/metadata and knowledge standardization, sharing, and
analysis. With hundreds of biological and biomedical ontologies developed, it has become …

Navigating the Landscape: A Comprehensive Review of Current Virus Databases

M Ritsch, NA Cassman, S Saghaei, M Marz - Viruses, 2023 - mdpi.com
Viruses are abundant and diverse entities that have important roles in public health,
ecology, and agriculture. The identification and surveillance of viruses rely on an …

Integrating advanced molecular technologies into public health

M Gwinn, DR MacCannell… - Journal of clinical …, 2017 - Am Soc Microbiol
Advances in laboratory and information technologies are transforming public health
microbiology. High-throughput genome sequencing and bioinformatics are enhancing our …