Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …

Abstract The WHO Classification of Tumors of Soft Tissue and Bone divides
rhabdomyosarcoma (RMS) into alveolar, embryonal, pleomorphic, and spindle …

Oncogenic KRAS (KRAS*) contributes to many cancer hallmarks. In colorectal cancer,
KRAS* suppresses antitumor immunity to promote tumor invasion and metastasis. Here, we …

Sarcoma represents a highly heterogeneous group of tumours. We report here the first
unbiased and systematic search for gene fusions combined with unsupervised expression …

Primary intraosseous rhabdomyosarcomas (RMSs) are extremely rare. Recently 2 studies
reported 4 cases of primary intraosseous RMS with EWSR1/FUS-TFCP2 gene fusions …

The TFCP2/Grainyhead family of transcription factors is divided into two distinct subfamilies,
one of which includes the Grainyhead-like 1-3 (GRHL1-3) proteins and the other consists of …

Highlights: Multi tyrosine kinase inhibitors licensed for HCC treatment. Multi kinase inhibitors
not licensed for HCC treatment. Inhibitors of Growth Factor Receptors. Small molecules …

Abstract Grainyhead (Grh)/CP2 transcription factors are highly conserved in multicellular
organisms as key regulators of epithelial differentiation, organ development and skin barrier …

Background The erythroblastosis virus E26 transforming sequences (ETS) family of
transcription factors consists of a highly conserved group of genes that play important roles …

Abstract AEG-1/MTDH/LYRIC has been shown to promote cancer progression and
development. Overexpression of AEG-1/MTDH/LYRIC correlates with angiogenesis …