Nucleic acid-assisted CRISPR-Cas systems for advanced biosensing and bioimaging
Nucleic acid molecules possess many superior properties, including high designability and
structural predictability, making them attractive biosensing and bioimaging tools. The …
structural predictability, making them attractive biosensing and bioimaging tools. The …
CRISPR/Cas Systems‐Inspired Nano/Biosensors for Detecting Infectious Viruses and Pathogenic Bacteria
Infectious pathogens cause severe human illnesses and great deaths per year worldwide.
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …
Photocontrolled crRNA activation enables robust CRISPR-Cas12a diagnostics
M Hu, Z Qiu, Z Bi, T Tian, Y Jiang… - Proceedings of the …, 2022 - National Acad Sciences
CRISPR diagnostics based on nucleic acid amplification faces barriers to its commercial
use, such as contamination risks and insufficient sensitivity. Here, we propose a robust …
use, such as contamination risks and insufficient sensitivity. Here, we propose a robust …
COVID-19 point-of-care diagnostics: present and future
Point-of-care (POC) detection technologies that enable decentralized, rapid, sensitive, low-
cost diagnostics of COVID-19 infection are urgently needed around the world. With many …
cost diagnostics of COVID-19 infection are urgently needed around the world. With many …
Smartphone-based SARS-CoV-2 and variants detection system using colorimetric DNAzyme reaction triggered by loop-mediated isothermal amplification (LAMP) with …
Coronavirus disease (COVID-19) has affected people for over two years. Moreover, the
emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has …
emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has …
A one-pot CRISPR/Cas13a-based contamination-free biosensor for low-cost and rapid nucleic acid diagnostics
F Hu, Y Liu, S Zhao, Z Zhang, X Li, N Peng… - Biosensors and …, 2022 - Elsevier
The pandemic due to the outbreak of 2019 coronavirus disease (COVID-19) caused by
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …
Sensitive and rapid on-site detection of SARS-CoV-2 using a gold nanoparticle-based high-throughput platform coupled with CRISPR/Cas12-assisted RT-LAMP
Y Zhang, M Chen, C Liu, J Chen, X Luo, Y Xue… - Sensors and Actuators B …, 2021 - Elsevier
The outbreak of corona virus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic. The high infectivity of …
syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic. The high infectivity of …
A CRISPR-based and post-amplification coupled SARS-CoV-2 detection with a portable evanescent wave biosensor
Y Yang, J Liu, X Zhou - Biosensors and Bioelectronics, 2021 - Elsevier
The continuing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infection, which causes coronavirus disease 2019 (COVID-19), has spread globally and …
2) infection, which causes coronavirus disease 2019 (COVID-19), has spread globally and …
Photoactivatable CRISPR/Cas12a strategy for one-pot DETECTR molecular diagnosis
Y Chen, X Xu, J Wang, Y Zhang, W Zeng… - Analytical …, 2022 - ACS Publications
As a golden partner of recombinase polymerase amplification (RPA), CRISPR/Cas12a has
been proven to solve the false-positive problem caused by nonspecific amplification …
been proven to solve the false-positive problem caused by nonspecific amplification …
Light‐Start CRISPR‐Cas12a Reaction with Caged crRNA Enables Rapid and Sensitive Nucleic Acid Detection
M Hu, R Liu, Z Qiu, F Cao, T Tian, Y Lu… - Angewandte …, 2023 - Wiley Online Library
The clustered regularly interspaced short palindromic repeats (CRISPR) system is a
promising platform for nucleic acid detection. Regulating the CRISPR reaction would be …
promising platform for nucleic acid detection. Regulating the CRISPR reaction would be …