[HTML][HTML] The contribution of Neanderthal introgression to modern human traits

PF Reilly, A Tjahjadi, SL Miller, JM Akey, S Tucci - Current Biology, 2022 - cell.com
Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

More than a decade of genetic research on the Denisovans

S Peyrégne, V Slon, J Kelso - Nature Reviews Genetics, 2024 - nature.com
Denisovans, a group of now extinct humans who lived in Eastern Eurasia in the Middle and
Late Pleistocene, were first identified from DNA sequences just over a decade ago. Only ten …

A Middle Pleistocene Denisovan molar from the Annamite chain of northern Laos

F Demeter, C Zanolli, KE Westaway… - Nature …, 2022 - nature.com
The Pleistocene presence of the genus Homo in continental Southeast Asia is primarily
evidenced by a sparse stone tool record and rare human remains. Here we report a Middle …

Decoding the human face: progress and challenges in understanding the genetics of craniofacial morphology

S Naqvi, H Hoskens, F Wilke… - Annual review of …, 2022 - annualreviews.org
Variations in the form of the human face, which plays a role in our individual identities and
societal interactions, have fascinated scientists and artists alike. Here, we review our current …

Differential DNA methylation of vocal and facial anatomy genes in modern humans

D Gokhman, M Nissim-Rafinia, L Agranat-Tamir… - Nature …, 2020 - nature.com
Abstract Changes in potential regulatory elements are thought to be key drivers of
phenotypic divergence. However, identifying changes to regulatory elements that underlie …

Evolution of homo in the middle and late Pleistocene

K Harvati, H Reyes-Centeno - Journal of Human Evolution, 2022 - Elsevier
Abstract The Middle and Late Pleistocene is arguably the most interesting period in human
evolution. This broad period witnessed the evolution of our own lineage, as well as that of …

Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution

D Gokhman, RM Agoglia, M Kinnebrew, W Gordon… - Nature …, 2021 - nature.com
Gene regulatory divergence is thought to play a central role in determining human-specific
traits. However, our ability to link divergent regulation to divergent phenotypes is limited …

The cis-regulatory effects of modern human-specific variants

CV Weiss, L Harshman, F Inoue, HB Fraser, DA Petrov… - elife, 2021 - elifesciences.org
The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ
between modern and archaic humans, the majority of which are noncoding. However, our …

Ghost introgression: spooky gene flow in the distant past

J Ottenburghs - Bioessays, 2020 - Wiley Online Library
Evolution is a continuous trial and error process in which most lineages go extinct without
leaving fossil remains. Many of these lineages would be closely related and occasionally …

Evolution of cranial capacity revisited: A view from the late Middle Pleistocene cranium from Xujiayao, China

XJ Wu, CJ Bae, M Friess, S Xing, S Athreya… - Journal of Human …, 2022 - Elsevier
Abstract The Late Middle Pleistocene hominin fossils from the Xujiayao site in northern
China have been closely studied in light of their morphological variability. However, all …