Effects of physical exercise and body weight on disease-specific outcomes of people with rheumatic and musculoskeletal diseases (RMDs): systematic reviews and …

JM Gwinnutt, M Wieczorek, G Cavalli, A Balanescu… - RMD open, 2022 - rmdopen.bmj.com
Background A European League Against Rheumatism (EULAR) taskforce was convened to
develop recommendations for lifestyle behaviours in rheumatic and musculoskeletal …

Axial alignment is a critical regulator of knee osteoarthritis

T Oláh, J Reinhard, MW Laschke, LKH Goebel… - Science Translational …, 2022 - science.org
Although osteoarthritis (OA), a leading cause of disability, has been associated with joint
malalignment, scientific translational evidence for this link is lacking. In a clinical case study …

Analysis of spatial osteochondral heterogeneity in advanced knee osteoarthritis exposes influence of joint alignment

S Haberkamp, T Oláh, P Orth, M Cucchiarini… - Science Translational …, 2020 - science.org
Osteoarthritis (OA) is considerably affected by joint alignment. Here, we investigate the
patterns of spatial osteochondral heterogeneity in patients with advanced varus knee OA …

[HTML][HTML] The morphology of proximal tibiofibular joint (PTFJ) predicts incident radiographic osteoarthritis: data from Osteoarthritis Initiative

J Chang, Z Zhu, W Han, Y Zhao, CK Kwoh… - Osteoarthritis and …, 2020 - Elsevier
Objective To determine whether the morphology of proximal tibiofibular joint (PTFJ) is
associated with increased risk of incident radiographic osteoarthritis (iROA) over 4 years in …

Patellofemoral alignment and geometry and early signs of osteoarthritis are associated in patellofemoral pain population

JFA Eijkenboom, RA van der Heijden… - … Journal of Medicine …, 2020 - Wiley Online Library
Background Patellofemoral pain (PFP) patients show increased prevalence of patellar
malalignment. Structural and alignment abnormalities of the patellofemoral joint (PFJ) may …

[HTML][HTML] Modulation of early osteoarthritis by tibiofemoral re-alignment in sheep

J Reinhard, T Oláh, MW Laschke, LKH Goebel… - Osteoarthritis and …, 2024 - Elsevier
Objective To investigate whether tibiofemoral alignment influences early knee osteoarthritis
(OA). We hypothesized that varus overload exacerbates early degenerative osteochondral …

Cartilage survival of the knee strongly depends on malalignment: a survival analysis from the Osteoarthritis Initiative (OAI)

M Faschingbauer, M Kasparek, W Waldstein… - Knee Surgery, Sports …, 2020 - Springer
Purpose Progression of osteoarthritis over time is poorly understood. The aim of the current
study was to establish a timeline of “cartilage survival rate” per subregion of the knee in …

Cartilage thickness in the medial compartment of the knee joint evaluated by MRI three-dimensional analysis correlates with weight-bearing line ratio and joint line …

N Ozeki, H Koga, T Nakamura, H Katagiri… - Journal of Orthopaedic …, 2024 - Elsevier
Purpose The correlation between cartilage thickness evaluated by 3D MRI and knee
alignment has not been elucidated. The study's purpose was to retrospectively verify …

Validation of a novel blinding method for measuring postoperative knee articular cartilage using magnetic resonance imaging

R Moyer, T Birmingham, F Eckstein, W Wirth… - … Resonance Materials in …, 2019 - Springer
Objectives To test PEEK implant-associated MRI artifacts, a method for blinding MRI
readers, the repeatability of cartilage thickness measures before and 6 weeks after high …

[HTML][HTML] Relationship between alignment and cartilage thickness in patients with non-traumatic and post-traumatic knee osteoarthritis

SM Robbins, F Abram, M Boily, JP Pelletier… - Osteoarthritis and …, 2019 - Elsevier
Objective To compare cartilage thickness between patients with non-traumatic and post-
traumatic knee osteoarthritis (OA) and healthy controls and to determine if disease severity …