[HTML][HTML] Unmet medical needs in chronic, non-communicable inflammatory skin diseases
H Ujiie, D Rosmarin, MP Schön, S Ständer… - Frontiers in …, 2022 - frontiersin.org
An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …
[HTML][HTML] The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets
R Maglie, F Solimani, D Didona, C Pipitò… - Frontiers in …, 2023 - frontiersin.org
Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …
[HTML][HTML] Treatment of rare inflammatory kidney diseases: drugs targeting the terminal complement pathway
M Anliker-Ort, J Dingemanse, J Van den Anker… - Frontiers in …, 2020 - frontiersin.org
The complement system comprises the frontline of the innate immune system. Triggered by
pathogenic surface patterns in different pathways, the cascade concludes with the formation …
pathogenic surface patterns in different pathways, the cascade concludes with the formation …
[HTML][HTML] The relevance of complement in pemphigoid diseases: a critical appraisal
Pemphigoid diseases are autoimmune chronic inflammatory skin diseases, which are
characterized by blistering of the skin and/or mucous membranes, and circulating and tissue …
characterized by blistering of the skin and/or mucous membranes, and circulating and tissue …
Evaluation of nomacopan for treatment of bullous pemphigoid: a phase 2a nonrandomized controlled trial
CD Sadik, H Rashid, CM Hammers… - Jama …, 2022 - jamanetwork.com
Importance Bullous pemphigoid is a difficult-to-treat autoimmune blistering skin disease that
predominantly affects older adults and is associated with an increased mortality rate …
predominantly affects older adults and is associated with an increased mortality rate …
[HTML][HTML] Milestones in personalized medicine in pemphigus and pemphigoid
Pemphigus and pemphigoid diseases are autoimmune bullous diseases characterized and
caused by autoantibodies targeting adhesion molecules in the skin and/or mucous …
caused by autoantibodies targeting adhesion molecules in the skin and/or mucous …
[HTML][HTML] C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita
CF Guerrero-Juarez, P Schilf, J Li, MP Zappia… - Frontiers in …, 2023 - frontiersin.org
Introduction Inflammatory epidermolysis bullosa acquisita (EBA) is characterized by a
neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the …
neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the …
[HTML][HTML] Resolution in bullous pemphigoid
Pemphigoid diseases are a group of autoimmune blistering skin diseases defined by an
immune response against certain components of the dermal-epidermal adhesion complex …
immune response against certain components of the dermal-epidermal adhesion complex …
[HTML][HTML] Bullous pemphygoid and novel therapeutic approaches
GM D'Agostino, G Rizzetto, A Marani, S Marasca… - Biomedicines, 2022 - mdpi.com
Bullous pemphigoid is a subepidermal blistering disease associated with autoantibodies
(auto-ab) to BP180 and BP230 which affects elderly patients, predominately. Although it is a …
(auto-ab) to BP180 and BP230 which affects elderly patients, predominately. Although it is a …
[HTML][HTML] Dapsone suppresses disease in preclinical murine models of pemphigoid diseases
S Murthy, P Schilf, S Patzelt, M Thieme… - Journal of Investigative …, 2021 - Elsevier
Epidermolysis bullosa acquisita and mucous membrane pemphigoid are autoimmune
blistering diseases characterized by mucocutaneous blisters elicited by an autoantibody …
blistering diseases characterized by mucocutaneous blisters elicited by an autoantibody …