Fat storage in adult mammals is a highly regulated process that involves the mobilization of
adipocyte progenitor cells (APCs) that differentiate to produce new adipocytes. Here we …

The CXXC domain, first identified as the reader of unmodified CpG dinucleotide, plays
important roles in epigenetic regulation by targeting various activities to CpG islands. Here …

CXXC domain-containing proteins are often involved in different biological processes, such
as cell proliferation and development, apoptosis, DNA repair, signaling transduction, and …

Iron deficiency (ID) is a widespread condition concomitant with disease and results in
systemic dysfunction of target tissues including skeletal muscle. Activated by ID …

Monoubiquitination plays a critical role as one of the largest histone post-translational
modifications (PTMs). Recent study has revealed that histone H2B monoubiquitination …

FBXL19 is a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases and is linked to
a variety of vital biological processes, such as cell proliferation, migration, and …

Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) requires a
resetting of the epigenome in order to facilitate a cell fate transition. Previous studies have …

CpG islands are gene regulatory elements associated with the majority of mammalian
promoters, yet how they regulate gene expression remains poorly understood. Here, we …

Background: Monoubiquitination plays a critical role as one of the largest histone post-
translational modifications (PTMs). Recent study has revealed that histone H2B …