Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Vinyl azides are highly versatile synthons that provide access to numerous N-heterocycles
and other functional groups. α-Substituted vinyl azides (azido vinylidenes) are a special …

The C− H functionalization strategy provides access to valuable molecules that previously
required convoluted synthetic attempts. Dual C− H unsymmetrical functionalization, with a …

A silver‐catalyzed intermolecular aminosulfonylation of terminal alkynes with sodium
sulfinates and TMSN3 is reported. This three‐component reaction proceeds through …

Azides are important intermediates in organic synthesis. They can function as precursors to
form amines, amides, quinolones, pyridines, triazoles, amidines, indoles, and so on …

Comprehensive Summary Yne‐allenes bearing both a C—C triple bond and an allene unit
are a class of focal substrates in organic synthesis, in view of their structure diversity, high …

Multicomponent reactions (MCRs) have emerged as an important branch in organic
synthesis for the creation of complex molecular structures from more than two starting …

Alkyne C C bond breaking, outside of alkyne metathesis, remains an underdeveloped area
in reaction discovery. Recently, nitrogenation has been reported to allow nitrile formation …

An unexpected metal-free C C triple bond cleavage, dioxygen activation, and reassembly
into tryptophol derivatives has been developed. This chemistry provides a novel, simple, and …

A new type of alanine triazole (ATA) ligand was found to be an efficient partner for the
stabilization of gold (III), thus rendering improved stability and high catalytic activities in …