This review deals with the roles of calcium ions and ATP in the control of the normal
functions of the different cell types in the exocrine pancreas as well as the roles of these …

Ionized calcium (Ca 2÷) is the most common signal transduction element in cells ranging
from bacteria to specialized neurons. Unlike many other second-messenger mo! ecules, Ca …

The ryanodine receptors (RyRs) are a family of Ca2+ release channels found on
intracellular Ca2+ storage/release organelles. The RyR channels are ubiquitously …

Ca2+ is a ubiquitous cellular signal. Altered expression of specific Ca2+ channels and
pumps are characterizing features of some cancers. The ability of Ca2+ to regulate both cell …

Since its introduction to Ca2+ signaling in 1997, 2‐aminoethoxydiphenyl borate (2‐APB)
has been used in many studies to probe for the involvement of inositol 1, 4, 5‐trisphosphate …

The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present
in all types of nerve cells. The ER is an interconnected, internally continuous system of …

The ryanodine receptor (RyR) is a high-conductance Ca2+ channel of the sarcoplasmic
reticulum in muscle and of the endoplasmic reticulum in other cells. In striated muscle fibers …

Ryanodine receptors (RyRs) are intracellular calcium release channels that participate in
controlling cytosolic calcium levels. At variance with the probably ubiquitous inositol 1, 4, 5 …

Cell death and dysfunction after traumatic brain injury (TBI) is caused by a primary phase,
related to direct mechanical disruption of the brain, and a secondary phase which consists of …

Fluxes in amounts of intracellular calcium ions are important determinants of gene
expression,,. So far, Ca2+-regulated kinases and phosphatases have been implicated in …