Emerging viruses and current strategies for vaccine intervention
During the past decade several notable viruses have suddenly emerged from obscurity or
anonymity to become serious global health threats, provoking concern regarding their …
anonymity to become serious global health threats, provoking concern regarding their …
Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control
S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - Signal transduction and …, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
Arenavirus glycan shield promotes neutralizing antibody evasion and protracted infection
R Sommerstein, L Flatz, MM Remy, P Malinge… - PLoS …, 2015 - journals.plos.org
Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans.
As a major impediment to vaccine development, delayed and weak neutralizing antibody …
As a major impediment to vaccine development, delayed and weak neutralizing antibody …
Structure of the Lassa virus glycan shield provides a model for immunological resistance
Lassa virus is an Old World arenavirus endemic to West Africa that causes severe
hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein …
hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein …
Recent advances in bunyavirus glycoprotein research: precursor processing, receptor binding and structure
RJG Hulswit, GC Paesen, TA Bowden, X Shi - Viruses, 2021 - mdpi.com
The Bunyavirales order accommodates related viruses (bunyaviruses) with segmented,
linear, single-stranded, negative-or ambi-sense RNA genomes. Their glycoproteins form …
linear, single-stranded, negative-or ambi-sense RNA genomes. Their glycoproteins form …
Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development
HJ Hallam, S Hallam, SE Rodriguez, ADT Barrett… - NPJ vaccines, 2018 - nature.com
Lassa fever (LF) is a zoonotic disease associated with acute and potentially fatal
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …
Zoonotic aspects of arenavirus infections
RN Charrel, X de Lamballerie - Veterinary microbiology, 2010 - Elsevier
To date, the International Committee for Taxonomy of Viruses recognizes that the family
Arenaviridae contains a unique genus Arenavirus that includes 22 viral species. There are …
Arenaviridae contains a unique genus Arenavirus that includes 22 viral species. There are …
[HTML][HTML] Lack of evidence for ribavirin treatment of Lassa fever in systematic review of published and unpublished studies
Ribavirin has been used widely to treat Lassa fever in West Africa since the 1980s.
However, few studies have systematically appraised the evidence for its use. We conducted …
However, few studies have systematically appraised the evidence for its use. We conducted …
Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot
M Mateo, S Reynard, X Carnec, A Journeaux… - Science translational …, 2019 - science.org
Lassa fever is a major threat in Western Africa. The large number of people living at risk for
this disease calls for the development of a vaccine against Lassa virus (LASV). We …
this disease calls for the development of a vaccine against Lassa virus (LASV). We …
Pathogenesis of Lassa fever in cynomolgus macaques
LE Hensley, MA Smith, JB Geisbert, EA Fritz… - Virology journal, 2011 - Springer
Background Lassa virus (LASV) infection causes an acute and sometimes fatal hemorrhagic
disease in humans and nonhuman primates; however, little is known about the development …
disease in humans and nonhuman primates; however, little is known about the development …