High-throughput genomic data in systematics and phylogenetics
High-throughput genomic sequencing is rapidly changing the field of phylogenetics by
decreasing the cost and increasing the quantity and rate of data collection by several orders …
decreasing the cost and increasing the quantity and rate of data collection by several orders …
Molecular Diversity of K+ Channels
K+ channel principal subunits are by far the largest and most diverse of the ion channels.
This diversity originates partly from the large number of genes coding for K+ channel …
This diversity originates partly from the large number of genes coding for K+ channel …
Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis
J Castresana - Molecular biology and evolution, 2000 - academic.oup.com
The use of some multiple-sequence alignments in phylogenetic analysis, particularly those
that are not very well conserved, requires the elimination of poorly aligned positions and …
that are not very well conserved, requires the elimination of poorly aligned positions and …
Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments
G Talavera, J Castresana - Systematic biology, 2007 - academic.oup.com
Alignment quality may have as much impact on phylogenetic reconstruction as the
phylogenetic methods used. Not only the alignment algorithm, but also the method used to …
phylogenetic methods used. Not only the alignment algorithm, but also the method used to …
Gaps as characters in sequence-based phylogenetic analyses
MP Simmons, H Ochoterena - Systematic biology, 2000 - JSTOR
In the analysis of sequence-based data matrices, the use of different methods of treating
gaps has been demonstrated to in? fluence the resulting phylogenetic hypothe? ses (eg …
gaps has been demonstrated to in? fluence the resulting phylogenetic hypothe? ses (eg …
GUIDANCE: a web server for assessing alignment confidence scores
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every
comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE …
comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE …
Can three incongruence tests predict when data should be combined?
CW Cunningham - Molecular Biology and Evolution, 1997 - academic.oup.com
Advocates of conditional combination have argued that testing for incongruence between
data partitions is an important step in data exploration. Unless the partitions have had …
data partitions is an important step in data exploration. Unless the partitions have had …
Phylogenomics: improving functional predictions for uncharacterized genes by evolutionary analysis
JA Eisen - Genome research, 1998 - genome.cshlp.org
The ability to accurately predict gene function based on gene sequence is an important tool
in many areas of biological research. Such predictions have become particularly important …
in many areas of biological research. Such predictions have become particularly important …
Molecular Systematics of the Eastern Fence Lizard (Sceloporus undulatus): A Comparison of Parsimony, Likelihood, and Bayesian Approaches
Phylogenetic analysis of large datasets using complex nucleotide substitution models under
a maximum likelihood framework can be computationally infeasible, especially when …
a maximum likelihood framework can be computationally infeasible, especially when …
A simple, fast, and accurate method of phylogenomic inference
The explosive growth of genomic data provides an opportunity to make increased use of
protein markers for phylogenetic inference. We have developed an automated pipeline for …
protein markers for phylogenetic inference. We have developed an automated pipeline for …