High-throughput genomic data in systematics and phylogenetics

EM Lemmon, AR Lemmon - Annual Review of Ecology …, 2013 - annualreviews.org
High-throughput genomic sequencing is rapidly changing the field of phylogenetics by
decreasing the cost and increasing the quantity and rate of data collection by several orders …

Molecular Diversity of K+ Channels

WA Coetzee, Y Amarillo, J Chiu, A Chow… - Annals of the New …, 1999 - Wiley Online Library
K+ channel principal subunits are by far the largest and most diverse of the ion channels.
This diversity originates partly from the large number of genes coding for K+ channel …

Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis

J Castresana - Molecular biology and evolution, 2000 - academic.oup.com
The use of some multiple-sequence alignments in phylogenetic analysis, particularly those
that are not very well conserved, requires the elimination of poorly aligned positions and …

Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments

G Talavera, J Castresana - Systematic biology, 2007 - academic.oup.com
Alignment quality may have as much impact on phylogenetic reconstruction as the
phylogenetic methods used. Not only the alignment algorithm, but also the method used to …

Gaps as characters in sequence-based phylogenetic analyses

MP Simmons, H Ochoterena - Systematic biology, 2000 - JSTOR
In the analysis of sequence-based data matrices, the use of different methods of treating
gaps has been demonstrated to in? fluence the resulting phylogenetic hypothe? ses (eg …

GUIDANCE: a web server for assessing alignment confidence scores

O Penn, E Privman, H Ashkenazy… - Nucleic acids …, 2010 - academic.oup.com
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every
comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE …

Can three incongruence tests predict when data should be combined?

CW Cunningham - Molecular Biology and Evolution, 1997 - academic.oup.com
Advocates of conditional combination have argued that testing for incongruence between
data partitions is an important step in data exploration. Unless the partitions have had …

Phylogenomics: improving functional predictions for uncharacterized genes by evolutionary analysis

JA Eisen - Genome research, 1998 - genome.cshlp.org
The ability to accurately predict gene function based on gene sequence is an important tool
in many areas of biological research. Such predictions have become particularly important …

Molecular Systematics of the Eastern Fence Lizard (Sceloporus undulatus): A Comparison of Parsimony, Likelihood, and Bayesian Approaches

AD Leaché, TW Reeder - Systematic biology, 2002 - academic.oup.com
Phylogenetic analysis of large datasets using complex nucleotide substitution models under
a maximum likelihood framework can be computationally infeasible, especially when …

A simple, fast, and accurate method of phylogenomic inference

M Wu, JA Eisen - Genome biology, 2008 - Springer
The explosive growth of genomic data provides an opportunity to make increased use of
protein markers for phylogenetic inference. We have developed an automated pipeline for …