One hundred years have passed since Warburg discovered alterations in cancer
metabolism, more than 70 years since Sidney Farber introduced anti-folates that …

Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

Despite recent progress in our understanding of the association between the gut
microbiome and colorectal cancer (CRC), multi-kingdom gut microbiome dysbiosis in CRC …

Background Besides featured glucose consumption, recent studies reveal that cancer cells
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …

Targeting tumor cell metabolism is an attractive form of therapy, as it may enhance treatment
response in therapy resistant cancers as well as mitigate treatment-related toxicities by …

Cancer cells require a massive supply of nutrients, including sugars and amino acids—the
upregulation of transporters for each nutrient contributes to meet the demand. Distinct from …

Simple Summary Dysregulated glutamine metabolism is one of the metabolic features
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …

The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …

Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …

Reprogramming of amino acid metabolism, sustained by oncogenic signaling, is crucial for
cancer cell survival under nutrient limitation. Here we discovered that missense mutant p53 …