[HTML][HTML] When pharmaceutical drugs become environmental pollutants: Potential neural effects and underlying mechanisms
Pharmaceutical drugs have become consumer products, with a daily use for some of them.
The volume of production and consumption of drugs is such that they have become …
The volume of production and consumption of drugs is such that they have become …
[HTML][HTML] Steroid transport, local synthesis, and signaling within the brain: roles in neurogenesis, neuroprotection, and sexual behaviors
N Diotel, TD Charlier… - Frontiers in …, 2018 - frontiersin.org
Sex steroid hormones are synthesized from cholesterol and exert pleiotropic effects notably
in the central nervous system. Pioneering studies from Baulieu and colleagues have …
in the central nervous system. Pioneering studies from Baulieu and colleagues have …
Zebrafish sex differentiation and gonad development: a review on the impact of environmental factors
D Santos, A Luzio, AM Coimbra - Aquatic toxicology, 2017 - Elsevier
Zebrafish (Danio rerio) is extensively used in research; however the mechanisms that
control this species sex determination are still poorly understood. In the latest decades, it …
control this species sex determination are still poorly understood. In the latest decades, it …
A review on sex steroid hormone estrogen receptors in mammals and fish
E Amenyogbe, G Chen, Z Wang, X Lu… - International journal …, 2020 - Wiley Online Library
Steroid hormones play essential roles in the reproductive biology of vertebrates. Estrogen
exercises its effect through estrogen receptors and is not only a female reproductive …
exercises its effect through estrogen receptors and is not only a female reproductive …
[HTML][HTML] Estrogenic effects of several BPA analogs in the developing zebrafish brain
J Cano-Nicolau, C Vaillant, E Pellegrini… - Frontiers in …, 2016 - frontiersin.org
Important set of studies have demonstrated the endocrine disrupting activity of Bisphenol A
(BPA). The present work aimed at defining estrogenic-like activity of several BPA structural …
(BPA). The present work aimed at defining estrogenic-like activity of several BPA structural …
[HTML][HTML] Direct and indirect effects of sex steroids on gonadotrope cell plasticity in the teleost fish pituitary
The pituitary gland controls many important physiological processes in vertebrates,
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …
[HTML][HTML] A comprehensive review of the neurobehavioral effects of bisphenol S and the mechanisms of action: New insights from in vitro and in vivo models
The normal brain development and function are delicately driven by an ever-changing
milieu of steroid hormones arising from fetal, placental, and maternal origins. This reliance …
milieu of steroid hormones arising from fetal, placental, and maternal origins. This reliance …
Zinc protects against lead-induced testicular damage via modulation of steroidogenic and xanthine oxidase/uric acid/caspase 3-mediated apoptotic signaling in male …
EE Besong, PJ Ashonibare, OO Obembe… - The Aging …, 2023 - Taylor & Francis
Aim This study evaluated the effect of lead, with or without zinc co-administration, on
steroidogenic and xanthine oxidase (XO)/uric acid (UA)/caspase 3-mediated apoptotic …
steroidogenic and xanthine oxidase (XO)/uric acid (UA)/caspase 3-mediated apoptotic …
Synthetic microfiber exposure negatively affects reproductive parameters in male medaka (Oryzias latipes)
MJ Kim, JA Kim, JA Song, KH Kho, CY Choi - General and Comparative …, 2023 - Elsevier
Microplastics not only accumulate in the bodies of fishes and cause damage to the organs,
but also cause many other problems, such as reduced reproductive capacity, by acting …
but also cause many other problems, such as reduced reproductive capacity, by acting …
[HTML][HTML] Brain aromatase modulates serotonergic neuron by regulating serotonin levels in zebrafish embryos and larvae
ZS Ulhaq, M Kishida - Frontiers in endocrinology, 2018 - frontiersin.org
Teleost fish are known to express two isoforms of P450 aromatase, a key enzyme for
estrogen synthesis. One of the isoforms, brain aromatase (AroB), cyp19a1b, is highly …
estrogen synthesis. One of the isoforms, brain aromatase (AroB), cyp19a1b, is highly …