Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature

AE Gauthier, RD Rotjan, JC Kagan - Open Biology, 2022 - royalsocietypublishing.org
Since the publication of the Janeway's Pattern Recognition hypothesis in 1989, study of
pathogen-associated molecular patterns (PAMPs) and their immuno-stimulatory activities …

Connectomes across development reveal principles of brain maturation

D Witvliet, B Mulcahy, JK Mitchell, Y Meirovitch… - Nature, 2021 - nature.com
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …

[HTML][HTML] Piwi/PRG-1 argonaute and TGF-β mediate transgenerational learned pathogenic avoidance

RS Moore, R Kaletsky, CT Murphy - Cell, 2019 - cell.com
The ability to inherit learned information from parents could be evolutionarily beneficial,
enabling progeny to better survive dangerous conditions. We discovered that, after C …

Distinct neural circuits for the formation and retrieval of episodic memories

DS Roy, T Kitamura, T Okuyama, SK Ogawa, C Sun… - Cell, 2017 - cell.com
The formation and retrieval of a memory is thought to be accomplished by activation and
reactivation, respectively, of the memory-holding cells (engram cells) by a common set of …

Inheritance of associative memories and acquired cellular changes in C. elegans

N Deshe, Y Eliezer, L Hoch, E Itskovits… - Nature …, 2023 - nature.com
Experiences have been shown to modulate behavior and physiology of future generations in
some contexts, but there is limited evidence for inheritance of associative memory in …

Neural architecture of hunger-dependent multisensory decision making in C. elegans

DD Ghosh, T Sanders, S Hong, LY McCurdy, DL Chase… - Neuron, 2016 - cell.com
Little is known about how animals integrate multiple sensory inputs in natural environments
to balance avoidance of danger with approach to things of value. Furthermore, the …

Host-microbe interactions and the behavior of Caenorhabditis elegans

DH Kim, SW Flavell - Journal of Neurogenetics, 2020 - Taylor & Francis
Microbes are ubiquitous in the natural environment of Caenorhabditis elegans. Bacteria
serve as a food source for C. elegans but may also cause infection in the nematode host …

[HTML][HTML] Neuromodulatory control of long-term behavioral patterns and individuality across development

S Stern, C Kirst, CI Bargmann - Cell, 2017 - cell.com
Animals generate complex patterns of behavior across development that may be shared or
unique to individuals. Here, we examine the contributions of developmental programs and …

Neuronal mitochondrial dynamics coordinate systemic mitochondrial morphology and stress response to confer pathogen resistance in C. elegans

LT Chen, CT Lin, LY Lin, JM Hsu, YC Wu, CL Pan - Developmental cell, 2021 - cell.com
Mitochondrial functions across different tissues are regulated in a coordinated fashion to
optimize the fitness of an organism. Mitochondrial unfolded protein response (UPR mt) can …