Glycopeptide enrichment and separation for protein glycosylation analysis

S Ongay, A Boichenko, N Govorukhina… - Journal of separation …, 2012 - Wiley Online Library
Protein glycosylation plays key roles in many biological processes. In addition, alterations in
protein glycosylation have been related to different diseases, as well as may affect the …

Functionalized magnetic nanoparticles for sample preparation in proteomics and peptidomics analysis

Y Li, X Zhang, C Deng - Chemical Society Reviews, 2013 - pubs.rsc.org
Sample preparation is a fundamental step in the proteomics and peptidomics workflow. Due
to their good biocompatibility, superparamagnetic property, and high binding capacity …

Hydrazide Functionalized Core–Shell Magnetic Nanocomposites for Highly Specific Enrichment of N-Glycopeptides

L Liu, M Yu, Y Zhang, C Wang, H Lu - ACS applied materials & …, 2014 - ACS Publications
In view of the biological significance of glycosylation for human health, profiling of
glycoproteome from complex biological samples is highly inclined toward the discovery of …

Synthesis and anti-melanoma activity of l-cysteine-coated iron oxide nanoparticles loaded with doxorubicin

LI Toderascu, LE Sima, S Orobeti, PE Florian… - Nanomaterials, 2023 - mdpi.com
In this study, we report on the synthesis of L-Cysteine (L-Cys)-coated magnetic iron oxide
nanoparticles (NPs) loaded with doxorubicin (Dox). The Fe3O4-L-Cys-Dox NPs were …

Interaction modes and approaches to glycopeptide and glycoprotein enrichment

CC Chen, WC Su, BY Huang, YJ Chen, HC Tai… - Analyst, 2014 - pubs.rsc.org
Protein glycosylation has received increased attention for its critical role in cell biology and
diseases. Developing new methodologies to discern phenotype-dependent glycosylation …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010

DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Development of versatile metal–organic framework functionalized magnetic graphene core–shell biocomposite for highly specific recognition of glycopeptides

J Wang, J Li, Y Wang, M Gao, X Zhang… - ACS Applied Materials …, 2016 - ACS Publications
Protein N-glycosylation is a ubiquitous and important post-translational modification that has
been involved in the development and progression of a series of human-related diseases …

Multilayer hydrophilic poly (phenol-formaldehyde resin)-coated magnetic graphene for boronic acid immobilization as a novel matrix for glycoproteome analysis

J Wang, Y Wang, M Gao, X Zhang… - ACS Applied Materials & …, 2015 - ACS Publications
Capturing glycopeptides selectively and efficiently from mixed biological samples has
always been critical for comprehensive and in-depth glycoproteomics analysis, but the lack …

Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay

M Kurogochi, T Matsushista, M Amano… - Molecular & Cellular …, 2010 - ASBMB
Despite increasing importance of protein glycosylation, most of the large-scale
glycoproteomics have been limited to profiling the sites of N-glycosylation. However, in …

Glycan analysis by reversible reaction to hydrazide beads and mass spectrometry

SJ Yang, H Zhang - Analytical chemistry, 2012 - ACS Publications
Investigation into glycoproteins and their associated glycans is the key to understanding the
function of glycoproteins in biological pathways and disease development. Current methods …