Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

C Widmann, S Gibson, MB Jarpe… - Physiological …, 1999 - journals.physiology.org
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …

Recent insights into Candida albicans biofilm resistance mechanisms

L Mathé, P Van Dijck - Current genetics, 2013 - Springer
Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …

Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero… - Nature, 2016 - nature.com
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

LA Walker, CA Munro, I De Bruijn, MD Lenardon… - PLoS …, 2008 - journals.plos.org
Echinocandins are a new generation of novel antifungal agent that inhibit cell wall β (1, 3)-
glucan synthesis and are normally cidal for the human pathogen Candida albicans …

Molecular organization of the cell wall of Candida albicans

FM Klis, P Groot, K Hellingwerf - Medical mycology, 2001 - Taylor & Francis
We have recently presented a molecular model of the cell wall of Saccharomyces
cerevisiae. Here we discuss the evidence that a similar model is also valid for Candida …

Stress adaptation in a pathogenic fungus

AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014 - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …

Mitogen-activated protein kinase pathways and fungal pathogenesis

X Zhao, R Mehrabi, JR Xu - Eukaryotic cell, 2007 - Am Soc Microbiol
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …

MAP kinases in fungal pathogens

JR Xu - Fungal Genetics and Biology, 2000 - Elsevier
MAP kinases in eukaryotic cells are well known for transducing a variety of extracellular
signals to regulate cell growth and differentiation. Recently, MAP kinases homologous to the …

The PKC, HOG and Ca2+ signalling pathways co‐ordinately regulate chitin synthesis in Candida albicans

CA Munro, S Selvaggini, I De Bruijn… - Molecular …, 2007 - Wiley Online Library
Chitin is an essential component of the fungal cell wall and its synthesis is under tight spatial
and temporal regulation. The fungal human pathogen Candida albicans has a four member …