Cellular collection by apheresis

A Padmanabhan - Transfusion, 2018 - Wiley Online Library
Cellular collection is an important and increasingly used apheresis procedure. These
collections are performed by leukocytapheresis, a procedure involving the removal of a …

Optimisation and quality control of cell processing for autologous stem cell transplantation

MJ Watts, DC Linch - British journal of haematology, 2016 - Wiley Online Library
Clinical practice and the technology of cell processing for autologous stem cell
transplantation has continued to evolve over the last two decades and merits review of …

Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients

EB Esrick, JP Manis, H Daley, C Baricordi… - Blood …, 2018 - ashpublications.org
Novel therapies for sickle cell disease (SCD) based on genetically engineered autologous
hematopoietic stem and progenitor cells (HSPCs) are critically dependent on a safe and …

[HTML][HTML] Effect of high-dose plerixafor on CD34+ cell mobilization in healthy stem cell donors: results of a randomized crossover trial

J Pantin, E Purev, X Tian, L Cook… - …, 2017 - ncbi.nlm.nih.gov
Hematopoietic stem cells can be mobilized from healthy donors using single-agent
plerixafor without granulocyte colony-stimulating factor and, following allogeneic …

Predicting successful hematopoietic stem cell collection in healthy allogeneic donors

S Kayser, RF Schlenk, M Steiner, H Klüter… - Transfusion Medicine …, 2023 - karger.com
Introduction: Collection of peripheral blood stem cells (PBSCs) from healthy donors is a well-
established process. We aimed to identify factors predictive of successful CD34+ PBSC …

Comparison between intermittent and continuous spectra optia leukapheresis systems for autologous peripheral blood stem cell collection

K Lisenko, P Pavel, T Bruckner… - Journal of clinical …, 2017 - Wiley Online Library
Terumo BCT recently introduced a new system for mononuclear cell (MNC) collection that
uses a Spectra Optia apheresis machine equipped with a redesigned disposable kit and …

Plerixafor is effective given either preemptively or as a rescue strategy in poor stem cell mobilizing patients with multiple myeloma

J Cheng, M Schmitt, P Wuchter, EC Buss… - …, 2015 - Wiley Online Library
Background Harvest of more than one CD 34+ stem cell transplant has become the
standard, to ensure the option for a second autologous transplantation in patients with …

Impact of mobilization strategies on peripheral blood stem cell collection efficiency and product quality: a retrospective single-center study

P Rajsp, M Branka, N Besson, A Tanzmann, N Worel - Cancers, 2022 - mdpi.com
Simple Summary We retrospectively reviewed data from cancer patients undergoing
peripheral blood stem cell (PBSC) collection following different mobilization regimens (with …

HPC‐A dose prediction on the Optia® cell separator based on a benchmark CE2 collection efficiency: promoting clinical efficiency, minimizing toxicity, and allowing …

AF Cousins, JE Sinclair, MJ Alcorn… - Journal of Clinical …, 2015 - Wiley Online Library
It has been shown that it is possible to predict the CD 34+ hematopoietic progenitor cell
dose from collection procedures on TerumoBCT COBE Spectra® cell separator platform …

Rescue stem cell mobilization with plerixafor economizes leukapheresis in patients with multiple myeloma

M Hundemer, M Engelhardt, T Bruckner… - Journal of clinical …, 2014 - Wiley Online Library
While extensive data demonstrated that plerixafor improves stem cell harvest in difficult‐to‐
mobilize patients, economic concerns limit a broader application. We retrospectively …