The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

Promoting bone regeneration and repairing defects are urgent and critical challenges in
orthopedic clinical practice. Research on bone substitute biomaterials is essential for …

Polysaccharide hydrogels are widely used in tissue engineering because of their superior
biocompatibility and low immunogenicity. However, many of these hydrogels are unrealistic …

Natural polymers have been extensively explored as the vehicles for encapsulation and
delivery of drugs and other bioactive molecules, which have attracted tremendous attention …

Plant polysaccharides represent a natural source material characterized by high ubiquity,
abundance and biological activities that can be utilised as organic matter in numerous …

Breast cancer is considered one of the utmost neoplastic diseases globally, with a high
death rate of patients. Over the last decades, many approaches have been studied to early …

Chitosan displays a dual function, acting as both an active ingredient and/or carrier for
pharmaceutical bioactive molecules and metal ions. Its hydroxyl-and amino-reactive groups …

The use of methods at molecular scale for the discovery of new potential active ligands, as
well as previously unknown binding sites for target proteins, is now an established reality …

The incidence rate of breast cancer in women is high, and this has caused a significant
health problem for society and public health providers.(p1) The epidemiological data …

Recent progresses in tissue engineering are directed towards the development of
technologies able to provide personalized scaffolds recreating the defect shape in a patient …