The extracellular matrix and the immune system: A mutually dependent relationship
TE Sutherland, DP Dyer, JE Allen - Science, 2023 - science.org
For decades, immunologists have studied the role of circulating immune cells in host
protection, with a more recent appreciation of immune cells resident within the tissue …
protection, with a more recent appreciation of immune cells resident within the tissue …
Neutrophils in cancer: heterogeneous and multifaceted
CC Hedrick, I Malanchi - Nature Reviews Immunology, 2022 - nature.com
Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …
important regulators of cancer. However, their functional importance has often been …
The principles of directed cell migration
S SenGupta, CA Parent, JE Bear - Nature Reviews Molecular Cell …, 2021 - nature.com
Cells have the ability to respond to various types of environmental cues, and in many cases
these cues induce directed cell migration towards or away from these signals. How cells …
these cues induce directed cell migration towards or away from these signals. How cells …
Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
Mucosal immune responses to infection and vaccination in the respiratory tract
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
Fluorescence-amplified nanocrystals in the second near-infrared window for in vivo real-time dynamic multiplexed imaging
Optical imaging in the second near-infrared window (NIR-II, 1,000–1,700 nm) holds great
promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging …
promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging …
COVID‐19 and neutrophils: the relationship between hyperinflammation and neutrophil extracellular traps
Coronavirus disease 2019 (COVID‐19) is a virus‐induced respiratory disease that may
progress to acute respiratory distress syndrome (ARDS) and is triggered by …
progress to acute respiratory distress syndrome (ARDS) and is triggered by …
A guide to chemokines and their receptors
CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
Neutrophils: New insights and open questions
Neutrophils are the first line of defense against bacteria and fungi and help combat parasites
and viruses. They are necessary for mammalian life, and their failure to recover after …
and viruses. They are necessary for mammalian life, and their failure to recover after …
Neutrophils as protagonists and targets in chronic inflammation
O Soehnlein, S Steffens, A Hidalgo… - Nature Reviews …, 2017 - nature.com
Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …
recruited to an inflamed tissue and have mainly been considered in the context of acute …