Genome-protecting compounds as potential geroprotectors
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
Acetyl-l-Carnitine Attenuates Arsenic-Induced Oxidative Stress and Hippocampal Mitochondrial Dysfunction
H Keshavarz-Bahaghighat, MR Sepand… - Biological trace element …, 2018 - Springer
Augmentation of mitochondrial oxidative stress through activating a series of deadly events
has implicated as the main culprit of arsenic toxicity and therapeutic approaches based on …
has implicated as the main culprit of arsenic toxicity and therapeutic approaches based on …
A novel strategy to predict carcinogenicity of antiparasitics based on a combination of DNA lesions and bacterial mutagenicity tests
Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is
requested by regulatory agencies. The bacterial mutagenicity test was considered having …
requested by regulatory agencies. The bacterial mutagenicity test was considered having …
Protective effects of simvastatin on cytotoxicity and oxidative stress in human gingival fibroblasts cells exposed to venlafaxine
S Kuhestani, M Shokrzadeh… - … of Medical Sciences, 2022 - jmums.mazums.ac.ir
Background and purpose: Venlafaxine is an antidepressant that belongs to the family of
selective serotonin and norepinephrine reuptake inhibitor (SNRIs) drugs. Recent studies …
selective serotonin and norepinephrine reuptake inhibitor (SNRIs) drugs. Recent studies …
L-carnitine as an adjuvant treatment in acute organophosphorus pesticides poisoning: a randomized clinical trial
Organophosphorus compounds are widely used pesticides. They are associated with a
significant risk of acute intoxication. Oxidative stress is a contributing factor of acute …
significant risk of acute intoxication. Oxidative stress is a contributing factor of acute …
Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine
LF Martins, WV Silva, NF Nascimento… - Arquivo Brasileiro de …, 2023 - SciELO Brasil
ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the
mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and …
mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and …
Mitigating impact of l-carnitine against dimethoate induction of hepatic and testicular genotoxicity in rats: the role of oxidative stress
Dimethoate (DM) is a widely used organophosphate insecticide in Egyptian fields with toxic
impacts on mammalians. This paper intends to evaluate the role of l-carnitine (LC) on DM …
impacts on mammalians. This paper intends to evaluate the role of l-carnitine (LC) on DM …
اثرات محافظتی سیمواستاتین بر سمیت سلولی و استرس اکسیداتیو سلول هاي فیبروبلاست لثه انسانی در مواجهه با داروي ونلافاکسین.
سینا کوهستانی, محمد شکرزاده… - … of Medical Sciences …, 2022 - search.ebscohost.com
Background and purpose: Venlafaxine is an antidepressant that belongs to the family of
selective serotonin and norepinephrine reuptake inhibitor (SNRIs) drugs. Recent studies …
selective serotonin and norepinephrine reuptake inhibitor (SNRIs) drugs. Recent studies …