Most anticancer treatments trigger tumor cell death through apoptosis, where initiation of
proteolytic action of caspase protein is a basic need. But under certain circumstances …

Parasitic diseases are still a huge problem for mankind. They are becoming the main cause
of chronic diseases in the world. Migration of the population, pollution of the natural …

Malaria caused by Plasmodium falciparum remains the leading single-agent cause of
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …

Background Cryptocaryon irritans, a common parasite in tropical and subtropical marine
teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was …

The family of apicomplexan specific proteins contains caspases–like proteins called
“metacaspases”. These enzymes are present in the malaria parasite but absent in human; …

The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils
and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to …

The Yca1 metacaspase was discovered due to its role in the regulation of apoptosis in
Saccharomyces cerevisiae. However, the mechanisms that drive apoptosis in yeast remain …

Aims Acquired drug resistance of Plasmodium is a global issue for the treatment of malaria.
There are various proteases in the genome of Plasmodium falciparum (P. falciparum) …

Malaria is an enormous threat to public health due to the emergence of Plasmodium
falciparum resistance to widely used anti-malarials, such as chloroquine. Additionally, the …

Introduction Malaria control is hindered by drug-resistant parasites, leading to a shortage of
effective drugs. There is a need to find new, better antimalarial drug. Traditional Chinese …