Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants

C Mas‐Moruno, B Su, MJ Dalby - Advanced healthcare …, 2019 - Wiley Online Library
In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Powder metallurgy with space holder for porous titanium implants: A review

A Rodriguez-Contreras, M Punset, JA Calero… - Journal of Materials …, 2021 - Elsevier
One of the biggest challenges in the biocompatibility of implantable metals is the prevention
of the stress shielding effect, which is related to the coupling of the bone-metal mechanical …

Porous surface with fusion peptides embedded in strontium titanate nanotubes elevates osteogenic and antibacterial activity of additively manufactured titanium alloy

B Wang, J Lan, H Qiao, L Xie, H Yang, H Lin… - Colloids and Surfaces B …, 2023 - Elsevier
It is still a big challenge in orthopedics to treat infected bone defects properly using medical
metals. The use of three-dimensional (3D) scaffold materials that simultaneously mimic the …

Multi-biofunction of antimicrobial peptide-immobilized silk fibroin nanofiber membrane: Implications for wound healing

DW Song, SH Kim, HH Kim, KH Lee, CS Ki, YH Park - Acta biomaterialia, 2016 - Elsevier
An antimicrobial peptide motif (Cys-KR12) originating from human cathelicidin peptide
(LL37) was immobilized onto electrospun SF nanofiber membranes using EDC/NHS and …

Polymer brush grafted antimicrobial peptide on hydroxyapatite nanorods for highly effective antibacterial performance

K Li, J Chen, Y Xue, T Ding, S Zhu, M Mao… - Chemical Engineering …, 2021 - Elsevier
Serious bacterial infection induces the failure of artificial implants. Covalent bonding of
antimicrobial peptides (AMPs) on implant surfaces can avoid the main shortcoming (blast …

“Dual-functional” strontium titanate nanotubes designed based on fusion peptides simultaneously enhancing anti-infection and osseointegration

B Wang, A Bian, F Jia, J Lan, H Yang, K Yan, L Xie… - Biomaterials …, 2022 - Elsevier
Currently, there is an increasing clinical demand for implants that effectively resist bacterial
infections while promoting osseointegration. In this study, the fusion peptide technology was …

Surface modified with a host defense peptide-mimicking β-peptide polymer kills bacteria on contact with high efficacy

Y Qian, F Qi, Q Chen, Q Zhang, Z Qiao… - … applied materials & …, 2018 - ACS Publications
Methicillin-resistant Staphylococcus aureus (MRSA) has been one of the major nosocomial
pathogens to cause frequent and serious infections that are associated with various …

Peptide‐based approaches to fight biofouling

GP Sakala, M Reches - Advanced Materials Interfaces, 2018 - Wiley Online Library
Biofouling is the undesirable accumulation of organisms such as bacteria, fungi, and
barnacles on surfaces. It is a serious problem in many areas of our lives including health …

Fusion peptide engineered “statically-versatile” titanium implant simultaneously enhancing anti-infection, vascularization and osseointegration

J Chen, G Hu, T Li, Y Chen, M Gao, Q Li, L Hao, Y Jia… - Biomaterials, 2021 - Elsevier
Although antimicrobial titanium implants can prevent biomaterial-associated infection (BAI)
in orthopedics, they display cytotoxicity and delayed osseointegration. Therefore, versatile …

Host defense peptide mimicking poly-β-peptides with fast, potent and broad spectrum antibacterial activities

Q Zhang, P Ma, J Xie, S Zhang, X Xiao, Z Qiao… - Biomaterials …, 2019 - pubs.rsc.org
Microbial infections have always been serious challenges to human health considering that
antibiotics almost inevitably induce microbial resistance. Therefore, it is urgent to develop a …