[HTML][HTML] Diagnosis and treatment of therapy-related acute myeloid leukemia

SA Strickland, N Vey - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Therapy-related acute myeloid leukemia (t-AML), defined as AML arising from prior
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …

[HTML][HTML] New drugs before, during, and after hematopoietic stem cell transplantation for patients with acute myeloid leukemia

R Mohty, R El Hamed, E Brissot, A Bazarbachi… - …, 2023 - ncbi.nlm.nih.gov
The treatment of acute myeloid leukemia (AML) has evolved over the past few years with the
advent of next-generation sequencing. Targeted therapies alone or in combination with low …

Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia

AH Matthews, AE Perl, SM Luger, AW Loren… - Blood …, 2022 - ashpublications.org
CPX-351 and venetoclax and azacitidine (ven/aza) are both indicated as initial therapy for
acute myeloid leukemia (AML) in older adults. In the absence of prospective randomized …

Real-world experience of CPX-351 as first-line treatment for patients with acute myeloid leukemia

C Rautenberg, F Stölzel, C Röllig, M Stelljes… - Blood Cancer …, 2021 - nature.com
To investigate the efficacy and toxicities of CPX-351 outside a clinical trial, we analyzed 188
patients (median age 65 years, range 26–80) treated for therapy-related acute myeloid …

What to use to treat AML: The role of emerging therapies

F Thol - Hematology, 2021 - ashpublications.org
The development and approval of novel substances have resulted in substantial
improvements in the treatment of acute myeloid leukemia (AML). In the current era of novel …

In-depth time-dependent analysis of the benefit of allo-HSCT for elderly patients with CR1 AML: a FILO study

R Devillier, E Forcade, A Garnier… - Blood …, 2022 - ashpublications.org
The benefit of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients
with acute myeloid leukemia (AML) aged> 60 years remains a matter of debate, notably …

[HTML][HTML] Real-world experience with CPX-351 in high-risk acute myeloid leukemia

RM Lemoli, P Montesinos, A Jain - Critical reviews in oncology/hematology, 2023 - Elsevier
Abstract CPX-351, a dual-drug liposomal encapsulation of daunorubicin/cytarabine, was
approved for newly diagnosed therapy-related acute myeloid leukemia (AML) and AML with …

Evolving therapeutic approaches for older patients with acute myeloid leukemia in 2021

I Urbino, C Secreto, M Olivi, V Apolito, S D'Ardia… - Cancers, 2021 - mdpi.com
Simple Summary The better understanding of disease biology, the availability of new
effective drugs and the increased awareness of patients' heterogeneity in terms of fitness …

Refining AML treatment: the role of genetics in response and resistance evaluation to new agents

A Halik, CM Arends, L Bullinger, F Damm, M Frick - Cancers, 2022 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is an aggressive cancer of the
hematopoietic system. At present, we know that AML is heterogeneous and varies from one …

Measurable residual disease in high-risk acute myeloid leukemia

T Cluzeau, RM Lemoli, J McCloskey, T Cooper - Cancers, 2022 - mdpi.com
Simple Summary Assessment of measurable residual disease (MRD) identifies small
numbers of acute myeloid leukemia (AML) cells that may remain after initiating treatment …