[HTML][HTML] Cardiac-specific overexpression of catalytically inactive corin reduces edema, contractile dysfunction, and death in mice with dilated cardiomyopathy

R Tripathi, RD Sullivan, THM Fan, AK Houng… - International Journal of …, 2019 - mdpi.com
Humans with dilated cardiomyopathy (DCM) and heart failure (HF) develop low levels of
corin, a multi-domain, cardiac-selective serine protease involved in natriuretic peptide …

[HTML][HTML] Falling corin and ANP activity levels accelerate development of heart failure and cardiac fibrosis

IP Gladysheva, RD Sullivan, GL Reed - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Despite the best available therapies, heart failure with reduced ejection fraction (HFrEF)
remains one of the leading causes of morbidity and mortality worldwide (1). Dilated …