Signal transduction originates at the membrane, where the clustering of signaling proteins is
a key step in transmitting a message. Membranes are difficult to study, and their influence on …

Scaling laws associated with critical points have the power to greatly simplify our description
of complex biophysical systems. For the general reader, we first review basic concepts and …

The observation of lateral phase separation in lipid bilayers has received considerable
attention, especially in connection to lipid raft phenomena in cells. It is widely accepted that …

Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …

Cellular membranes exhibit a variety of controlled curvatures, with filopodia, microvilli, and
mitotic cleavage furrows being only a few of many examples. Coupling between local …

Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into
cells. Some have evolved to use specific lipids in the plasma membrane as their receptors …

This article summarizes a variety of physical mechanisms proposed in the literature, which
can generate micro-and nanodomains in multicomponent lipid bilayers and biomembranes …

In model lipid membranes with phase coexistence, domain sizes distribute in a very wide
range, from the nanometer (reported in vesicles and supported films) to the micrometer …

We have found modulated phase morphology in a particular region of composition within the
liquid-ordered+ liquid-disordered coexistence region in the four-component lipid bilayer …

The interest in membrane heterogeneity started with two biological questions: how is the
plasma membrane organized on a microscopic scale and what is the influence of this …