Melatonin: Physiological effects in humans
B Claustrat, J Leston - Neurochirurgie, 2015 - Elsevier
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal light/dark conditions. The endogenous rhythm of secretion is generated …
night under normal light/dark conditions. The endogenous rhythm of secretion is generated …
The neuroprotective role of melatonin in neurological disorders
BS Alghamdi - Journal of neuroscience research, 2018 - Wiley Online Library
Melatonin is a neurohormone secreted from the pineal gland and has a wide‐ranging
regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in …
regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in …
The basic physiology and pathophysiology of melatonin
B Claustrat, J Brun, G Chazot - Sleep medicine reviews, 2005 - Elsevier
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal environmental conditions. The endogenous rhythm of secretion is …
night under normal environmental conditions. The endogenous rhythm of secretion is …
Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans
DJ Dijk, CA Czeisler - Neuroscience letters, 1994 - Elsevier
The contribution of the circadian pacemaker and the sleep homeostat to sleep tendency and
consolidation was quantified by forced desynchrony of the sleep-wake cycle from the …
consolidation was quantified by forced desynchrony of the sleep-wake cycle from the …
Bright light therapy: improved sensitivity to its effects on rest-activity rhythms in Alzheimer patients by application of nonparametric methods
EJW Van Someren, DF Swaab… - Chronobiology …, 1999 - Taylor & Francis
Sleep-wake rhythm disturbances in patients with Alzheimer's disease (AD) make a strong
demand on caregivers and are among the most important reasons for institutionalization …
demand on caregivers and are among the most important reasons for institutionalization …
Pediatric craniopharyngiomas: classification and treatment according to the degree of hypothalamic involvement
Object The current treatment of craniopharyngiomas is evolving into one of a multimodal
approach in which the aim is disease control and improved preservation of quality of life …
approach in which the aim is disease control and improved preservation of quality of life …
Circadian rest—activity rhythm disturbances in Alzheimer's disease
EJW Van Someren, EEO Hagebeuk, C Lijzenga… - Biological …, 1996 - Elsevier
Previous studies showed circadian rhythm disturbances in patients with Alzheimer's
disease. Rest-activity rhythm disturbances manifest themselves through a fragmentation of …
disease. Rest-activity rhythm disturbances manifest themselves through a fragmentation of …
Invited Review: Integration of human sleep-wake regulation and circadian rhythmicity
DJ Dijk, SW Lockley - Journal of applied physiology, 2002 - journals.physiology.org
The human sleep-wake cycle is generated by a circadian process, originating from the
suprachiasmatic nuclei, in interaction with a separate oscillatory process: the sleep …
suprachiasmatic nuclei, in interaction with a separate oscillatory process: the sleep …
Circadian rhythms: basic neurobiology and clinical applications
RY Moore MD - Annual review of medicine, 1997 - annualreviews.org
▪ Abstract Circadian rhythms are major features of adaptation to our environment. In
mammals, circadian rhythms are generated and regulated by a circadian timing system. This …
mammals, circadian rhythms are generated and regulated by a circadian timing system. This …
Regulation and functional correlates of slow wave sleep
DJ Dijk - Journal of Clinical Sleep Medicine, 2009 - jcsm.aasm.org
to a parasympathetic dominance during SWS. 13, 14 Disruption of SWS can lead to a shift in
autonomic balance and associated changes in the response to glucose challenges. In fact …
autonomic balance and associated changes in the response to glucose challenges. In fact …