Predicting the stability of mutant proteins by computational approaches: an overview

A Marabotti, B Scafuri, A Facchiano - Briefings in Bioinformatics, 2021 - academic.oup.com
A very large number of computational methods to predict the change in thermodynamic
stability of proteins due to mutations have been developed during the last 30 years, and …

Deep learning for load forecasting: Sequence to sequence recurrent neural networks with attention

L Sehovac, K Grolinger - Ieee Access, 2020 - ieeexplore.ieee.org
The biggest contributor to global warming is energy production and use. Moreover, a push
for electrical vehicle and other economic developments are expected to further increase …

Protein function analysis through machine learning

C Avery, J Patterson, T Grear, T Frater, DJ Jacobs - Biomolecules, 2022 - mdpi.com
Machine learning (ML) has been an important arsenal in computational biology used to
elucidate protein function for decades. With the recent burgeoning of novel ML methods and …

Primary sequence based protein–protein interaction binder generation with transformers

J Wu, E Paquet, HL Viktor, W Michalowski - Complex & Intelligent Systems, 2024 - Springer
The design of binder proteins for specific target proteins using deep learning is a
challenging task that has a wide range of applications in both designing therapeutic …

Estimating the effect of single-point mutations on protein thermodynamic stability and analyzing the mutation landscape of the p53 protein

A Banerjee, P Mitra - Journal of chemical information and …, 2020 - ACS Publications
Nonsynonymous single-nucleotide polymorphisms often result in altered protein stability
while playing crucial roles both in the evolution process and in the development of human …

Semi-Supervised Semantic Segmentation Network for Point Clouds Based on 3D Shape

L Zhang, K Zhang - Applied Sciences, 2023 - mdpi.com
The semantic segmentation of point clouds has significant applications in fields such as
autonomous driving, robot vision, and smart cities. As LiDAR technology continues to …

Integrating Deep Learning with Structural Bioinformatics using Next-Generation Protein Stability Prediction

K Merriliance, N Soundiraraj - 2024 International Conference …, 2024 - ieeexplore.ieee.org
Protein stability refers to the propensity of a protein molecule to maintain its native folded
structure under various environmental conditions. Understanding protein stability is crucial …

Deep Learning for Protein-Protein Interaction Prediction and Protein Design

J Wu - 2023 - ruor.uottawa.ca
Protein–protein interactions (PPI) play a fundamental role in many biochemical functions
such as signal transduction, cellular organization, and cell cycle progression. Laboratory …

Giliuoju mokymusi grįstas diakritinių ženklų atstatymas lietuvių kalbai

L Pakalniškis - 2022 - epubl.ktu.edu
Abstract [eng] The amount of text data on the Internet is continuously increasing. However,
some online users are making mistakes when writing text. In case of Lithuanian language …

Biomolecular language processing for drug-target affinity prediction

R Özçelik - 2022 - 193.140.201.98
Finding high-affinity protein-chemical pairs is a prominent stage of the drug discovery
pipeline. However, the number of available proteins and chemicals forms an experimentally …