Abstract Exportin 1 (XPO1), also known as chromosome region maintenance protein 1,
plays a crucial role in maintaining cellular homeostasis via the regulated export of a range of …

Covering: 2011–July 2016 Myxobacteria are a rich source for structurally diverse secondary
metabolites with intriguing biological activities. Here we report on new natural products that …

Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the
skin remain largely unknown. We investigated the signal transduction pathway and …

Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …

Nuclear transport receptors of the karyopherin superfamily of proteins transport
macromolecules from one compartment to the other and are critical for both cell physiology …

Myxobacteria are Gram-negative eubacteria and they thrive in a variety of habitats including
soil rich in organic matter, rotting wood, animal dung and marine environment. Myxobacteria …

This study aimed to screen novel anticancer strategies from FDA-approved non-cancer
drugs and identify potential biomarkers and therapeutic targets for colorectal cancer (CRC) …

Bacteria are rich in a wide variety of secondary metabolites, such as pigments, alkaloids,
antibiotics, and others. These bioactive microbial products serve a great application in …

Infectious diseases are a major global concern and despite major advancements in medical
research, still cause significant morbidity and mortality. Progress in antiviral therapy is …

Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the
establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly …