Cell sources for cultivated meat: applications and considerations throughout the production workflow

J Reiss, S Robertson, M Suzuki - International Journal of Molecular …, 2021 - mdpi.com
Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …

Microcarriers for upscaling cultured meat production

V Bodiou, P Moutsatsou, MJ Post - Frontiers in nutrition, 2020 - frontiersin.org
Due to the considerable environmental impact and the controversial animal welfare
associated with industrial meat production, combined with the ever-increasing global …

[HTML][HTML] Mesenchymal stromal cells derived from various tissues: biological, clinical and cryopreservation aspects

LA Marquez-Curtis, A Janowska-Wieczorek… - Cryobiology, 2015 - Elsevier
Originally isolated from bone marrow, mesenchymal stromal cells (MSCs) have since been
obtained from various fetal and post-natal tissues and are the focus of an increasing number …

Integrating biomaterials and food biopolymers for cultured meat production

S Ng, M Kurisawa - Acta Biomaterialia, 2021 - Elsevier
Cultured meat has recently achieved mainstream prominence due to the emergence of
societal and industrial interest. In contrast to animal-based production of traditional meat, the …

Large‐scale expansion of human mesenchymal stem cells

MNFB Hassan, MD Yazid, MHM Yunus… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells with strong immunosuppressive
property that renders them an attractive source of cells for cell therapy. MSCs have been …

Influence of microenvironment on mesenchymal stem cell therapeutic potency: from planar culture to microcarriers

AC Tsai, R Jeske, X Chen, X Yuan, Y Li - Frontiers in bioengineering …, 2020 - frontiersin.org
Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Bovine myoblast cell production in a microcarriers-based system

S Verbruggen, D Luining, A van Essen, MJ Post - Cytotechnology, 2018 - Springer
For several tissue engineering applications, in particular food products, scaling up culture of
mammalian cells is a necessary task. The prevailing method for large scale cell culture is the …

Attachment and detachment strategies in microcarrier-based cell culture technology: A comprehensive review

S Derakhti, SH Safiabadi-Tali, G Amoabediny… - Materials Science and …, 2019 - Elsevier
Achieving a high cell density of animal cells is a prerequisite for different medical
applications such as cell therapy, tissue engineering, and vaccine production. Microcarrier …

Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds

PS Couto, MC Rotondi, A Bersenev, CJ Hewitt… - Biotechnology …, 2020 - Elsevier
Human mesenchymal stem/stromal cells (hMSCs) present a key therapeutic cellular
intervention for use in cell and gene therapy (CGT) applications due to their …

Mesenchymal stromal cell infusion to treat steroid-refractory acute GvHD III/IV after hematopoietic stem cell transplantation

GM Dotoli, GC De Santis, MD Orellana… - Bone marrow …, 2017 - nature.com
Acute GvHD (aGvHD) is a life-threatening complication of hematopoietic stem cell
transplantation. Frontline therapy for aGvHD consists of corticosteroid administration …