Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Advanced neuroimaging techniques in epilepsy

JS Duncan, K Trimmel - Current Opinion in Neurology, 2022 - journals.lww.com
Improved structural MRI increases detection of abnormalities that may underlie epilepsy.
Diffusion, structural and functional MRI indicate the widespread associations of epilepsy …

Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions

A Chari, KK Seunarine, X He, MM Tisdall… - Communications …, 2022 - nature.com
Network control theory provides a framework by which neurophysiological dynamics of the
brain can be modelled as a function of the structural connectome constructed from diffusion …

[HTML][HTML] Human anterior thalamic stimulation evoked cortical potentials align with intrinsic functional connectivity

D Wu, FL Schaper, G Jin, L Qi, J Du, X Wang, Y Wang… - Neuroimage, 2023 - Elsevier
Characterizing human thalamocortical network is fundamental for understanding a vast
array of human behaviors since the thalamus plays a central role in cortico-subcortical …

The anterior and centromedian thalamus: anatomy, function, and dysfunction in epilepsy

NM Warsi, H Yan, H Suresh, SM Wong, ON Arski… - Epilepsy Research, 2022 - Elsevier
The thalamus is a densely connected collection of nuclei that play a critical role in gating
information flow across the neocortex. Through diffuse reciprocal cortico-thalamo-cortical …

Advancing thalamic neuromodulation in epilepsy: Bridging adult data to pediatric care

D Samanta, G Aungaroon, GW Albert, C Karakas… - Epilepsy Research, 2024 - Elsevier
Thalamic neuromodulation has emerged as a treatment option for drug-resistant epilepsy
(DRE) with widespread and/or undefined epileptogenic networks. While deep brain …

[HTML][HTML] The role of thalamic nuclei in genetic generalized epilepsies

A Lüttjohann, G van Luijtelaar - Epilepsy research, 2022 - Elsevier
There is no doubt on the participation of the thalamus in the various types of genetic
generalized epilepsies as evidenced by multiple non-invasive imaging studies in humans as …

Neuroimaging and thalamic connectomics in epilepsy neuromodulation

EH Middlebrooks, X He, SS Grewal, SS Keller - Epilepsy Research, 2022 - Elsevier
Neuromodulation is an increasingly utilized therapy for the treatment of people with drug-
resistant epilepsy. To date, the most common and effective target has been the thalamus …

Functional brain connectivity in children with focal epilepsy: A systematic review of functional MRI studies

X Feng, RJ Piper, F Prentice, JD Clayden… - … : European Journal of …, 2024 - Elsevier
Epilepsy is increasingly recognised as a brain network disorder and many studies have
investigated functional connectivity (FC) in children with epilepsy using functional MRI …

Deep brain stimulation of the anterior nuclei of the thalamus in focal epilepsy

B Deutschová, I Rektor - Clinical Neurophysiology, 2022 - Elsevier
Objective To review the therapeutic effects of deep brain stimulation of the anterior nuclei of
the thalamus (ANT-DBS) and the predictors of its effectiveness, safety, and adverse effects …