[HTML][HTML] HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection
PW Hunt, E Sinclair, B Rodriguez… - The Journal of …, 2014 - academic.oup.com
Background. While inflammation predicts mortality in treated human immunodeficiency virus
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …
[HTML][HTML] Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated
with sustained elevated levels of immune activation and inflammation. However, the …
with sustained elevated levels of immune activation and inflammation. However, the …
HIV-associated neurocognitive disorder
DB Clifford, BM Ances - The Lancet infectious diseases, 2013 - thelancet.com
Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
Immunologic biomarkers, morbidity, and mortality in treated HIV infection
PW Hunt, SA Lee, MJ Siedner - The Journal of infectious …, 2016 - academic.oup.com
Despite marked improvements in the modern treatment era, human immunodeficiency virus
(HIV)–infected individuals, particularly those who initiated antiretroviral therapy (ART) at …
(HIV)–infected individuals, particularly those who initiated antiretroviral therapy (ART) at …
Microbial translocation in HIV infection: causes, consequences and treatment opportunities
NG Sandler, DC Douek - Nature Reviews Microbiology, 2012 - nature.com
Systemic immune activation is increased in HIV-infected individuals, even in the setting of
virus suppression with antiretroviral therapy. Although numerous factors may contribute …
virus suppression with antiretroviral therapy. Although numerous factors may contribute …
Microbial translocation, immune activation, and HIV disease
NR Klatt, NT Funderburg, JM Brenchley - Trends in microbiology, 2013 - cell.com
The advent of combination antiretroviral therapy (cART) has significantly improved the
prognosis of human immunodeficiency virus (HIV)-infected individuals. However, individuals …
prognosis of human immunodeficiency virus (HIV)-infected individuals. However, individuals …
Residual immune dysregulation syndrome in treated HIV infection
MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …
function and decreasing dramatically the mortality and morbidity due to the opportunistic …
Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection
Objective: Here we evaluated whether neurocognitive disorders in HIV-infected individuals
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …