Gut-gonad perturbations in type-1 diabetes mellitus: Role of dysbiosis, oxidative stress, inflammation and energy-dysbalance

A Panghal, G Jena - Current Diabetes Reviews, 2024 - ingentaconnect.com
Type 1 diabetes mellitus is a major metabolic disorder that affects people of all age groups
throughout the world. It is responsible for the alterations in male gonadal physiology in …

Spatiotemporal variations of vascular endothelial growth factor in the brain of diabetic cognitive impairment

Q Yin, J Ma, X Han, H Zhang, F Wang, P Zhuang… - Pharmacological …, 2021 - Elsevier
Although it is feared that diabetes-induced cognitive impairment (DCI) will become a major
clinical problem worldwide in the future, its detailed pathological mechanism is not well …

MicroRNA‑126 suppresses the proliferation and migration of endothelial cells in experimental diabetic retinopathy by targeting polo‑like kinase 4

Y Zheng, Y Liu, L Wang, H Xu, Z Lu… - International …, 2021 - spandidos-publications.com
As a specific microvascular complication of diabetes, diabetic retinopathy (DR) causes
severe visual impairment in patients with diabetes. The expression of microRNA‑126 …

Rosuvastatin attenuates airway inflammation and remodeling in a chronic allergic asthma model through modulation of the AMPKα signaling pathway

L Zhang, FY Huang, SZ Dai, L Wang, X Zhou… - Plos one, 2024 - journals.plos.org
The efficacy of rosuvastatin in reducing allergic inflammation has been established.
However, its potential to reduce airway remodeling has yet to be explored. This study aimed …

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

F Baganha, RCM de Jong, EA Peters, W Voorham… - Angiogenesis, 2021 - Springer
Objective Statins pleiotropically provide additional benefits in reducing atherosclerosis, but
their effects on intraplaque angiogenesis (IPA) and hemorrhage (IPH) remain unclear …

Ellagic acid inhibits proinflammatory intermediary manufacture by suppressing NF-κB/Akt, VEGF and activating Nrf-2/Caspase-3 signaling pathways in rat testicular …

A Aslan, O Gok, S Beyaz, H Uslu, F Erman… - Toxicology …, 2022 - Taylor & Francis
Ellagic acid (EA) has protective effect on testicular damage and this natural compound
decreases oxidative damage. The present study aims to examine the preventive effect of …

Transcription factor FOXP1 mediates vascular endothelial dysfunction in diabetic retinopathy

Y Zhou, Y Xuan, Y Liu, J Zheng, X Jiang… - Graefe's Archive for …, 2022 - Springer
Background Diabetic retinopathy (DR) is still the fastest growing cause of blindness in
working aged adults, and its typical characteristics are endothelial cell dysfunction and …

D-ribose-L-cysteine improves hormonal imbalance, spermatogenic dysregulation, and redox status in streptozotocin-diabetic rats

VO Ukwenya, TS Olawuyi, SA Adelakun… - Comparative Clinical …, 2020 - Springer
D-ribose-L-cysteine is a pro-drug that is derived from L-cysteine which is reported to
upsurge the cellular levels of glutathione. Diabetes mellitus is a metabolic disease that …

Hypoxia, NSAIDs, and autism: A biocultural analysis of stressors in gametogenesis

S Burke - American Journal of Human Biology, 2024 - Wiley Online Library
Cultural and generational trends have increasingly favored “anti‐inflammatory” action,
innovating a new class of analgesic, non‐steroidal anti‐inflammatory drugs (NSAIDs) in the …

[PDF][PDF] Uluslararası dergilerde Türk araştırmacılar tarafından yapılan “Erkek ve Kadın Cinsel Sağlığı”,“Erkek İnfertilitesi”,“Prostat hastalıkları” ve “Erkek Genital Sistemi …

A Altunkol, Ş Erdoğan, A Tuli - Biomed Pharmacother, 2018 - jag.journalagent.com
1. Abat D, Bayazıt Y, Açıkalın A, Dağlıoğlu K, Yenilmez ED, Altunkol A, Erdoğan Ş, Tuli A.
Beneficial effects of rolipram, a phosphodiesterase 4 specific inhibitor, on testicular …