Biofilm matrixome: extracellular components in structured microbial communities
Biofilms consist of microbial communities embedded in a 3D extracellular matrix. The matrix
is composed of a complex array of extracellular polymeric substances (EPS) that contribute …
is composed of a complex array of extracellular polymeric substances (EPS) that contribute …
Detection and characterization of bacterial biofilms and biofilm-based sensors
Microbial biofilms have caused serious concerns in healthcare, medical, and food industries
because of their intrinsic resistance against conventional antibiotics and cleaning …
because of their intrinsic resistance against conventional antibiotics and cleaning …
Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics
O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
The non-attached biofilm aggregate
Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …
following the five-step model of development. Initial biofilm research focused on surface …
[HTML][HTML] Unraveling antimicrobial resistance using metabolomics
M Kok, L Maton, M van der Peet, T Hankemeier… - Drug Discovery …, 2022 - Elsevier
The emergence of antimicrobial resistance (AMR) in bacterial pathogens represents a
global health threat. The metabolic state of bacteria is associated with a range of genetic …
global health threat. The metabolic state of bacteria is associated with a range of genetic …
The structure–function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment
M Lichtenberg, TH Jakobsen, M Kühl… - FEMS microbiology …, 2022 - academic.oup.com
Pseudomonas aeruginosa is a human pathogen associated with both acute and chronic
infections. While intensively studied, the basic mechanisms enabling the long-term survival …
infections. While intensively studied, the basic mechanisms enabling the long-term survival …
Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa
Bacteria in biofilms are embedded in extracellular matrix and display low metabolic activity,
partly due to insufficient diffusive exchange of metabolic substrate. The extracellular matrix …
partly due to insufficient diffusive exchange of metabolic substrate. The extracellular matrix …
Functionalized Bioink with Optical Sensor Nanoparticles for O2 Imaging in 3D‐Bioprinted Constructs
Research on 3D bioprinting of living cells has strong focus on printable biocompatible
materials and monitoring of cell growth in printed constructs, while cell metabolism is mostly …
materials and monitoring of cell growth in printed constructs, while cell metabolism is mostly …
Think outside the box: 3D bioprinting concepts for biotechnological applications–recent developments and future perspectives
F Krujatz, S Dani, J Windisch, J Emmermacher… - Biotechnology …, 2022 - Elsevier
Abstract 3D bioprinting–the fabrication of geometrically complex 3D structures from
biocompatible materials containing living cells using additive manufacturing technologies–is …
biocompatible materials containing living cells using additive manufacturing technologies–is …
[HTML][HTML] A review of chemosensors and biosensors for monitoring biofilm dynamics
Biofilms form complex structures that are ubiquitous in natural environments and can cause
chronic infections which are difficult to treat. While much is known about biofilms, many …
chronic infections which are difficult to treat. While much is known about biofilms, many …